| Reaction Details |
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 | Report a problem with these data |
| Target | Chitin synthase 3 |
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| Ligand | BDBM50089557 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_932677 (CHEMBL3070434) |
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| IC50 | 1035±n/a nM |
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| Citation |  TBA Med Chem Res22:1762-1772 (2013) Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Chitin synthase 3 |
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| Name: | Chitin synthase 3 |
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| Synonyms: | 2.4.1.16 | CHS3 | CHS3_CANAX | Chitin synthase 3 | Chitin-UDP acetyl-glucosaminyl transferase 3 | Class-IV chitin synthase 3 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 136214.76 |
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| Organism: | Candida albicans |
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| Description: | ChEMBL_106712 |
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| Residue: | 1213 |
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| Sequence: | MSNFRDSSSPRRGYSEFDPESGEGLGRKKSLIRPERSRMDESHPRFHYTQVANQESNHIK
VQPSSTGVDPRKSNELSTSRSHLSNYATPPHQEEEEDEGIPLMDIHNASPNVSSDQNNDL
KGGREVYGLNDEINDYGSSPKKNQVISSSRPMNNEKPAKPKHDIYFWKVYCYAITFWAPA
PLLKLFGLPTKDRQFAWREKIGLISCILYVGAFVAYLTFGFTKTVCSSQVVRTQINHVNG
GYLIINGRAYDLTSSQHPKAAGIQAGSNVLYPPMNAGGKDASFLFQNVNGNCKGLIKPRD
NCSIPYDGDELAWYMPCRLFNQDGSTKPNNTFAYYKGWACHTSETARDAYYKLKVNGDVY
FTWDDVKNSSRNLVVYSGNVLDLDLINWIETDDVTYPELFDKLRDDETYRGLDISLVLTN
SEERQAARCLTEIIKVGSIDTDTIGCIASKVVLYMSLVFILSVVVVKFIMACWFKWVTSR
KQGATMYDSKAWAKRNREIEDWVDHDHGIGAEVKTVPVKARANYKAAKTNRQSVFHRAQK
LSLGPNADLSQYYDNPNALSKTFKYTTMSTQAALLGRNGYGKRGNNANKSVSGGFNGRQS
NLYLTDQGSSTDLLNRPVSSYNPFDSMGDDSIVINGLSPDIIHPDVVPQPPVEYQPFGYP
LAHTINLVTCYSEDEEGIRITLDSIATTDYPNSHKLILVICDGIIKGSGNDETTPDIVLD
MMSDLTVPRDEVEAYSYVAVAQGSKRHNMAKVYAGFYKYNDETVPPEKQQRIPMITIVKC
GTPEEASAPKPGNRGKRDSQIILMSFLQKVVFDERMTSLEYEMLQSIWRITGLMAEFYEI
VLMVDADTKVFPDSLTHMVAEMVKDPTIMGLCGETKISNKAQTWVTAIQVFEYYISHHQA
KAFESIFGGVTCLPGCFCMYRIKAPKGSDGYWVPILANPDIVERYSDNVVDTLHRKNLLL
LGEDRYLSSLMLRTFPTRKQVFVPKAACKTVVPDKFKVLLSQRRRWINSTVHNLFELVLV
KDLCGTFCFSMQFVIFIELIGTLVLPAAITFTIYVIIVAIVSKPTPVMSLVLLAVIFGLP
GCLIVITVSSLSYLVYFVIYLFALPIWNFVLPSYAYWKFDDFSWGETRTVAGGDKGDHSA
VEGKFDSSKIAMKRWREWERERRSTENRKQQQQQQLTNNSSNNLAVPGAAWDPSNTGGNL
IDDLSQGSSSGSS
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| BDBM50089557 |
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| n/a |
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| Name | BDBM50089557 |
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| Synonyms: | 5-[Butyl-((E)-6,6-dimethyl-hept-2-en-4-ynyl)-amino]-3,4-dihydro-1H-quinolin-2-one | CHEMBL285056 |
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| Type | Small organic molecule |
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| Emp. Form. | C22H30N2O |
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| Mol. Mass. | 338.4864 |
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| SMILES | CCCCN(C\C=C\C#CC(C)(C)C)c1cccc2NC(=O)CCc12 |
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| Structure | 
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