| Reaction Details |
|---|
 | Report a problem with these data |
| Target | RNA-directed RNA polymerase |
|---|
| Ligand | BDBM50191539 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_932863 (CHEMBL3074361) |
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| IC50 | 31200000±n/a nM |
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| Citation |  TBA Med Chem Res22:1866-1883 (2013) Article |
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| More Info.: | Get all data from this article, Assay Method |
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| |
| RNA-directed RNA polymerase |
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| Name: | RNA-directed RNA polymerase |
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| Synonyms: | 2.7.7.48 | NS5B | RNA-directed RNA polymerase |
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| Type: | PROTEIN |
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| Mol. Mass.: | 13231.83 |
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| Organism: | Hepatitis C virus genotype 1 |
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| Description: | ChEMBL_106647 |
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| Residue: | 121 |
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| Sequence: | RCFDSTVTENDIRVEESIYQCCDLDPQARVAIKSLTERLYVGGPFTNSRGENCGYRRCRA
SGVLTTRCGNTLTCYMKAQAACRAARLRDCTMLVSGDDLVVICESAGAQEDAASLRAFTE
A
|
|
|
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| BDBM50191539 |
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| n/a |
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| Name | BDBM50191539 |
|---|
| Synonyms: | 2-{4-[4'-chloro-4-(isobutyrylmethylamino)biphenyl-2-ylmethoxy]-2-fluorophenyl}-1-cyclohexyl-1H-benzimidazole-5-carboxylic acid | CHEMBL212363 |
|---|
| Type | Small organic molecule |
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| Emp. Form. | C38H37ClFN3O4 |
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| Mol. Mass. | 654.169 |
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| SMILES | CC(C)C(=O)N(C)c1ccc(c(COc2ccc(-c3nc4cc(ccc4n3C3CCCCC3)C(O)=O)c(F)c2)c1)-c1ccc(Cl)cc1 |
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| Structure | 
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