| Reaction Details |
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 | Report a problem with these data |
| Target | Sigma non-opioid intracellular receptor 1 |
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| Ligand | BDBM50033842 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_201264 (CHEMBL804882) |
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| IC50 | 92.8±n/a nM |
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| Citation |  Perrone, R; Berardi, F; Colabufo, NA; Leopoldo, M; Tortorella, V; Fiorentini, F; Olgiati, V; Ghiglieri, A; Govoni, S High affinity and selectivity on 5-HT1A receptor of 1-aryl-4-[1-tetralin)alkyl]piperazines. 2. J Med Chem38:942-9 (1995) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| Sigma non-opioid intracellular receptor 1 |
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| Name: | Sigma non-opioid intracellular receptor 1 |
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| Synonyms: | Aging-associated gene 8 protein | OPRS1 | SGMR1_HUMAN | SIG-1R | SIGMAR1 | SR-BP | SR31747-binding protein | SRBP | Sigma 1-type opioid receptor | Sigma opioid receptor | Sigma1R | hSigmaR1 |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 25124.85 |
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| Organism: | Homo sapiens (Human) |
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| Description: | Q99720 |
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| Residue: | 223 |
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| Sequence: | MQWAVGRRWAWAALLLAVAAVLTQVVWLWLGTQSFVFQREEIAQLARQYAGLDHELAFSR
LIVELRRLHPGHVLPDEELQWVFVNAGGWMGAMCLLHASLSEYVLLFGTALGSRGHSGRY
WAEISDTIISGTFHQWREGTTKSEVFYPGETVVHGPGEATAVEWGPNTWMVEYGRGVIPS
TLAFALADTVFSTQDFLTLFYTLRSYARGLRLELTTYLFGQDP
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| BDBM50033842 |
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| n/a |
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| Name | BDBM50033842 |
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| Synonyms: | 1-(2-Methoxy-phenyl)-4-[4-(7-methoxy-1,2,3,4-tetrahydro-naphthalen-1-yl)-butyl]-piperazine | CHEMBL172363 |
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| Type | Small organic molecule |
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| Emp. Form. | C26H36N2O2 |
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| Mol. Mass. | 408.5762 |
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| SMILES | COc1ccc2CCCC(CCCCN3CCN(CC3)c3ccccc3OC)c2c1 |
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| Structure | 
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