| Reaction Details |
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 | Report a problem with these data |
| Target | Transcription factor 7-like 2 |
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| Ligand | BDBM50249236 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_938101 (CHEMBL2328061) |
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| Ki | 18000±n/a nM |
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| Citation |  Zhang, M; Catrow, JL; Ji, H High-Throughput Selectivity Assays for Small-Molecule Inhibitors of ?-Catenin/T-Cell Factor Protein-Protein Interactions. ACS Med Chem Lett4:306-11 (2013) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Transcription factor 7-like 2 |
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| Name: | Transcription factor 7-like 2 |
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| Synonyms: | HMG box transcription factor 4 | T-cell factor 4 | T-cell-specific transcription factor 4 | TCF-4 | TCF4 | TCF7L2 | TF7L2_HUMAN | hTCF-4 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 67939.08 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_107937 |
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| Residue: | 619 |
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| Sequence: | MPQLNGGGGDDLGANDELISFKDEGEQEEKSSENSSAERDLADVKSSLVNESETNQNSSS
DSEAERRPPPRSESFRDKSRESLEEAAKRQDGGLFKGPPYPGYPFIMIPDLTSPYLPNGS
LSPTARTLHFQSGSTHYSAYKTIEHQIAVQYLQMKWPLLDVQAGSLQSRQALKDARSPSP
AHIVSNKVPVVQHPHHVHPLTPLITYSNEHFTPGNPPPHLPADVDPKTGIPRPPHPPDIS
PYYPLSPGTVGQIPHPLGWLVPQQGQPVYPITTGGFRHPYPTALTVNASMSRFPPHMVPP
HHTLHTTGIPHPAIVTPTVKQESSQSDVGSLHSSKHQDSKKEEEKKKPHIKKPLNAFMLY
MKEMRAKVVAECTLKESAAINQILGRRWHALSREEQAKYYELARKERQLHMQLYPGWSAR
DNYGKKKKRKRDKQPGETNEHSECFLNPCLSLPPITDLSAPKKCRARFGLDQQNNWCGPC
RRKKKCVRYIQGEGSCLSPPSSDGSLLDSPPPSPNLLGSPPRDAKSQTEQTQPLSLSLKP
DPLAHLSMMPPPPALLLAEATHKASALCPNGALDLPPAALQPAAPSSSIAQPSTSSLHSH
SSLAGTQPQPLSLVTKSLE
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| BDBM50249236 |
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| n/a |
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| Name | BDBM50249236 |
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| Synonyms: | (R)-1-(4,9-dihydroxy-12-((R)-2-((4-hydroxyphenoxy)carbonyloxy)propyl)-2,6,7,11-tetramethoxy-3,10-dioxo-3,10-dihydroperylen-1-yl)propan-2-yl benzoate | CHEMBL460433 |
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| Type | Small organic molecule |
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| Emp. Form. | C44H38O14 |
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| Mol. Mass. | 790.7641 |
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| SMILES | COc1cc(=O)c2c(O)c(OC)c(C[C@@H](C)OC(=O)Oc3ccc(O)cc3)c3c4c(C[C@@H](C)OC(=O)c5ccccc5)c(OC)c(O)c5c4c(c(OC)cc5=O)c1c23 |r| |
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| Structure | 
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