| Reaction Details |
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 | Report a problem with these data |
| Target | DNA primase |
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| Ligand | BDBM50034952 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_81580 (CHEMBL689340) |
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| IC50 | >2000±n/a nM |
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| Citation |  Crute, JJ; Lehman, IR; Gambino, J; Yang, TF; Medveczky, P; Medveczky, M; Khan, NN; Mulder, C; Monroe, J; Wright, GE Inhibition of herpes simplex virus type 1 helicase-primase by (dichloroanilino)purines and -pyrimidines. J Med Chem38:1820-5 (1995) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| DNA primase |
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| Name: | DNA primase |
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| Synonyms: | DNA helicase/primase complex protein | PRIM_HHV11 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 114429.27 |
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| Organism: | Human herpesvirus 1 (strain 17) (HHV-1) (Human herpes simplex virus1) |
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| Description: | ChEMBL_84513 |
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| Residue: | 1058 |
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| Sequence: | MGQEDGNRGERRAAGTPVEVTALYATDGCVITSSIALLTNSLLGAEPVYIFSYDAYTHDG
RADGPTEQDRFEESRALYQASGGLNGDSFRVTFCLLGTEVGGTHQARGRTRPMFVCRFER
ADDVAALQDALAHGTPLQPDHIAATLDAEATFALHANMILALTVAINNASPRTGRDAAAA
QYDQGASLRSLVGRTSLGQRGLTTLYVHHEVRVLAAYRRAYYGSAQSPFWFLSKFGPDEK
SLVLTTRYYLLQAQRLGGAGATYDLQAIKDICATYAIPHAPRPDTVSAASLTSFAAITRF
CCTSQYARGAAAAGFPLYVERRIAADVRETSALEKFITHDRSCLRVSDREFITYIYLAHF
ECFSPPRLATHLRAVTTHDPNPAASTEQPSPLGREAVEQFFCHVRAQLNIGEYVKHNVTP
RETVLDGDTAKAYLRARTYAPGALTPAPAYCGAVDSATKMMGRLADAEKLLVPRGWPAFA
PASPGEDTAGGTPPPQTCGIVKRLLRLAATEQQGPTPPAIAALIRNAAVQTPLPVYRISM
VPTGQAFAALAWDDWARITRDARLAEAVVSAEAAAHPDHGALGRRLTDRIRAQGPVMPPG
GLDAGGQMYVNRNEIFNGALAITNIILDLDIALKEPVPFRRLHEALGHFRRGALAAVQLL
FPAARVDPDAYPCYFFKSACRPGPASVGSGSGLGNDDDGDWFPCYDDAGDEEWAEDPGAM
DTSHDPPDDEVAYFDLCHEVGPTAEPRETDSPVCSCTDKIGLRVCMPVPAPYVVHGSLTM
RGVARVIQQAVLLDRDFVEAIGSYVKNFLLIDTGVYAHGHSLRLPYFAKIAPDGPACGRL
LPVFVIPPACKDVPAFVAAHADPRRFHFHAPPTYLASPREIRVLHSLGGDYVSFFERKAS
RNALEHFGRRETLTEVLGRYNVQPDAGGTVEGFASELLGRIVACIETHFPEHAGEYQAVS
VRRAVSKDDWVLLQLVPVRGTLQQSLSCLRFKHGRASRATARTFVALSVGANNRLCVSLC
QQCFAAKCDSNRLHTLFTIDAGTPCSPSVPCSTSQPSS
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| BDBM50034952 |
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| n/a |
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| Name | BDBM50034952 |
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| Synonyms: | 6-(3,5-Dichloro-phenylamino)-1H-pyrimidine-2,4-dione | CHEMBL298714 |
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| Type | Small organic molecule |
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| Emp. Form. | C10H7Cl2N3O2 |
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| Mol. Mass. | 272.087 |
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| SMILES | Clc1cc(Cl)cc(Nc2cc(=O)[nH]c(=O)[nH]2)c1 |
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| Structure | 
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