| Reaction Details |
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 | Report a problem with these data |
| Target | Platelet-activating factor receptor |
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| Ligand | BDBM50035565 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_155133 (CHEMBL764095) |
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| IC50 | 17000±n/a nM |
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| Citation |  Houlihan, WJ; Munder, PG; Handley, DA; Cheon, SH; Parrino, VA Antitumor activity of 5-aryl-2,3-dihydroimidazo[2,1-a]isoquinolines. J Med Chem38:234-40 (1995) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| Platelet-activating factor receptor |
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| Name: | Platelet-activating factor receptor |
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| Synonyms: | PAF Platelet activating factor | PAF-R | PAFR | PTAFR | PTAFR_HUMAN | Platelet activating factor receptor | Platelet-activating factor receptor |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 39219.60 |
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| Organism: | Homo sapiens (Human) |
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| Description: | PAF Platelet activating factor PTAFR HUMAN::P25105 |
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| Residue: | 342 |
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| Sequence: | MEPHDSSHMDSEFRYTLFPIVYSIIFVLGVIANGYVLWVFARLYPCKKFNEIKIFMVNLT
MADMLFLITLPLWIVYYQNQGNWILPKFLCNVAGCLFFINTYCSVAFLGVITYNRFQAVT
RPIKTAQANTRKRGISLSLVIWVAIVGAASYFLILDSTNTVPDSAGSGNVTRCFEHYEKG
SVPVLIIHIFIVFSFFLVFLIILFCNLVIIRTLLMQPVQQQRNAEVKRRALWMVCTVLAV
FIICFVPHHVVQLPWTLAELGFQDSKFHQAINDAHQVTLCLLSTNCVLDPVIYCFLTKKF
RKHLTEKFYSMRSSRKCSRATTDTVTEVVVPFNQIPGNSLKN
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| BDBM50035565 |
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| n/a |
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| Name | BDBM50035565 |
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| Synonyms: | 5-(3,4-Dichloro-phenyl)-2,3-dihydro-imidazo[2,1-a]isoquinoline | CHEMBL310866 |
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| Type | Small organic molecule |
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| Emp. Form. | C17H12Cl2N2 |
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| Mol. Mass. | 315.197 |
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| SMILES | Clc1ccc(cc1Cl)C1=Cc2ccccc2C2=NCCN12 |t:9,18| |
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| Structure | 
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