| Reaction Details |
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 | Report a problem with these data |
| Target | Cannabinoid receptor 2 |
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| Ligand | BDBM50491596 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_959211 (CHEMBL2383566) |
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| Ki | 2.7±n/a nM |
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| Citation |  Aghazadeh Tabrizi, M; Baraldi, PG; Saponaro, G; Moorman, AR; Romagnoli, R; Preti, D; Baraldi, S; Ruggiero, E; Tintori, C; Tuccinardi, T; Vincenzi, F; Borea, PA; Varani, K Discovery of 7-oxopyrazolo[1,5-a]pyrimidine-6-carboxamides as potent and selective CB(2) cannabinoid receptor inverse agonists. J Med Chem56:4482-96 (2013) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Cannabinoid receptor 2 |
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| Name: | Cannabinoid receptor 2 |
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| Synonyms: | CANNABINOID CB2 | CB-2 | CB2 | CNR2_RAT | Cannabinoid CB2 receptor | Cannabinoid receptor | Cnr2 | rCB2 |
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| Type: | Enzyme |
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| Mol. Mass.: | 39366.68 |
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| Organism: | Rattus norvegicus (Rat) |
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| Description: | Q9QZN9 |
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| Residue: | 360 |
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| Sequence: | MAGCRELELTNGSNGGLEFNPMKEYMILSDAQQIAVAVLCTLMGLLSALENVAVLYLILS
SQRLRRKPSYLFIGSLAGADFLASVIFACNFVIFHVFHGVDSRNIFLLKIGSVTMTFTAS
VGSLLLTAVDRYLCLCYPPTYKALVTRGRALVALGVMWVLSALISYLPLMGWTCCPSPCS
ELFPLIPNDYLLGWLLFIAILFSGIIYTYGYVLWKAHQHVASLAEHQDRQVPGIARMRLD
VRLAKTLGLVMAVLLICWFPALALMGHSLVTTLSDKVKEAFAFCSMLCLVNSMINPIIYA
LRSGEIRSAAQHCLTGWKKYLQGLGSEGKEEAPKSSVTETEAEVKTTTGPGSRTPGCSNC
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| BDBM50491596 |
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| n/a |
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| Name | BDBM50491596 |
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| Synonyms: | CHEMBL2381786 |
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| Type | Small organic molecule |
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| Emp. Form. | C28H34N4O2 |
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| Mol. Mass. | 458.5952 |
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| SMILES | CCCCCn1cc(C(=O)NC23CC4CC(CC(C4)C2)C3)c(=O)n2nc(cc12)-c1ccccc1 |TLB:14:15:19:13.18.12,THB:16:15:18.17.19:12| |
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| Structure | 
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