| Reaction Details |
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 | Report a problem with these data |
| Target | Cannabinoid receptor 2 |
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| Ligand | BDBM50491840 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_960429 (CHEMBL2389080) |
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| IC50 | 1.7±n/a nM |
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| Citation |  Kusakabe, K; Iso, Y; Tada, Y; Sakagami, M; Morioka, Y; Chomei, N; Shinonome, S; Kawamoto, K; Takenaka, H; Yasui, K; Hamana, H; Hanasaki, K Selective CB2 agonists with anti-pruritic activity: discovery of potent and orally available bicyclic 2-pyridones. Bioorg Med Chem21:3154-63 (2013) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Cannabinoid receptor 2 |
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| Name: | Cannabinoid receptor 2 |
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| Synonyms: | CANNABINOID CB2 | CB-2 | CB2 | CB2A | CB2B | CNR2 | CNR2_HUMAN | CX5 | Cannabinoid CB2 receptor | Cannabinoid receptor 2 (CB2) | Cannabinoid receptor 2 (CB2R) | hCB2 |
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| Type: | G Protein-Coupled Receptor (GPCR) |
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| Mol. Mass.: | 39690.94 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P34972 |
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| Residue: | 360 |
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| Sequence: | MEECWVTEIANGSKDGLDSNPMKDYMILSGPQKTAVAVLCTLLGLLSALENVAVLYLILS
SHQLRRKPSYLFIGSLAGADFLASVVFACSFVNFHVFHGVDSKAVFLLKIGSVTMTFTAS
VGSLLLTAIDRYLCLRYPPSYKALLTRGRALVTLGIMWVLSALVSYLPLMGWTCCPRPCS
ELFPLIPNDYLLSWLLFIAFLFSGIIYTYGHVLWKAHQHVASLSGHQDRQVPGMARMRLD
VRLAKTLGLVLAVLLICWFPVLALMAHSLATTLSDQVKKAFAFCSMLCLINSMVNPVIYA
LRSGEIRSSAHHCLAHWKKCVRGLGSEAKEEAPRSSVTETEADGKITPWPDSRDLDLSDC
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| BDBM50491840 |
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| n/a |
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| Name | BDBM50491840 |
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| Synonyms: | CHEMBL2387186 |
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| Type | Small organic molecule |
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| Emp. Form. | C24H32N2O2 |
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| Mol. Mass. | 380.5231 |
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| SMILES | CCCCn1c2CCCCCCc2cc(C(=O)NCCc2ccccc2)c1=O |
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| Structure | 
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