| Reaction Details |
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 | Report a problem with these data |
| Target | Mu-type opioid receptor |
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| Ligand | BDBM50491882 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_961553 (CHEMBL2388584) |
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| Ki | 0.052000±n/a nM |
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| Citation |  Watanabe, Y; Kitazawa, S; Nemoto, T; Hirayama, S; Iwai, T; Fujii, H; Nagase, H Design and synthesis of novel opioid ligands with an azabicyclo[2.2.2]octane skeleton having a 7-amide side chain and their pharmacologies. Bioorg Med Chem21:3032-50 (2013) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Mu-type opioid receptor |
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| Name: | Mu-type opioid receptor |
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| Synonyms: | M-OR-1 | MOR-1 | Mor | OPIATE Mu | OPRM_MOUSE | Opioid receptors; mu and delta | Oprm | Oprm1 |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 44431.62 |
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| Organism: | MOUSE |
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| Description: | OPIATE Mu OPRM1 MOUSE::P42866 |
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| Residue: | 398 |
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| Sequence: | MDSSAGPGNISDCSDPLAPASCSPAPGSWLNLSHVDGNQSDPCGPNRTGLGGSHSLCPQT
GSPSMVTAITIMALYSIVCVVGLFGNFLVMYVIVRYTKMKTATNIYIFNLALADALATST
LPFQSVNYLMGTWPFGNILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRT
PRNAKIVNVCNWILSSAIGLPVMFMATTKYRQGSIDCTLTFSHPTWYWENLLKICVFIFA
FIMPVLIITVCYGLMILRLKSVRMLSGSKEKDRNLRRITRMVLVVVAVFIVCWTPIHIYV
IIKALITIPETTFQTVSWHFCIALGYTNSCLNPVLYAFLDENFKRCFREFCIPTSSTIEQ
QNSARIRQNTREHPSTANTVDRTNHQLENLEAETAPLP
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| BDBM50491882 |
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| n/a |
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| Name | BDBM50491882 |
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| Synonyms: | CHEMBL3215908 |
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| Type | Small organic molecule |
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| Emp. Form. | C30H37Cl2N3O4 |
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| Mol. Mass. | 574.538 |
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| SMILES | Cl.Cl.[H][C@@]12Oc3c4c(C[C@@]5([H])N(CC6CC6)CC[C@]14[C@@]51CC[C@@]2(O)[C@H](CC(=O)NCc2ccccc2)N1)ccc3O |r,THB:25:24:3.18:20.21,12:11:19:6.8.7| |
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| Structure | 
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