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| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | D(1A) dopamine receptor | ||
| Ligand | BDBM50010686 | ||
| Substrate/Competitor | n/a | ||
| Meas. Tech. | ChEMBL_58343 (CHEMBL671958) | ||
| IC50 | 5.6±n/a nM | ||
| Citation |  Knoerzer, TA; Nichols, DE; Brewster, WK; Watts, VJ; Mottola, D; Mailman, RB Dopaminergic benzo[a]phenanthridines: resolution and pharmacological evaluation of the enantiomers of dihydrexidine, the full efficacy D1 dopamine receptor agonist. J Med Chem37:2453-60 (1994) [PubMed] | ||
| More Info.: | Get all data from this article, Assay Method | ||
| D(1A) dopamine receptor | |||
| Name: | D(1A) dopamine receptor | ||
| Synonyms: | DOPAMINE D1 | DRD1_RAT | Dopamine D1 high | Dopamine D1 low | Dopamine receptor | Dopamine receptor D1 | Dopamine1-like | Drd1 | Drd1a | ||
| Type: | Enzyme Catalytic Domain | ||
| Mol. Mass.: | 49429.75 | ||
| Organism: | RAT | ||
| Description: | P18901 | ||
| Residue: | 446 | ||
| Sequence: |
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| BDBM50010686 | |||
| n/a | |||
| Name | BDBM50010686 | ||
| Synonyms: | (6aR,12bS)-10,11-Dihydroxy-5,6,6a,7,8,12b-hexahydro-benzo[a]phenanthridinium | (6aR,12bS)-5,6,6a,7,8,12b-Hexahydro-benzo[a]phenanthridine-10,11-diol | 10,11-Dihydroxy-5,6,6a,7,8,12b-hexahydro-benzo[a]phenanthridinium(DHX) | 5,6,6a,7,8,12b-Hexahydro-benzo[a]phenanthridine-10,11-diol | CHEMBL25856 | dihydrexidine | ||
| Type | Small organic molecule | ||
| Emp. Form. | C17H17NO2 | ||
| Mol. Mass. | 267.3224 | ||
| SMILES | Oc1cc2CC[C@H]3NCc4ccccc4[C@@H]3c2cc1O | ||
| Structure | 
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