| Reaction Details |
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 | Report a problem with these data |
| Target | D(2) dopamine receptor |
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| Ligand | BDBM50036927 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_61573 (CHEMBL673374) |
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| IC50 | 5.2±n/a nM |
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| Citation |  Norman, MH; Rigdon, GC; Navas, F; Cooper, BR Cyclic benzamides as mixed dopamine D2/serotonin 5-HT2 receptor antagonists: potential atypical antipsychotic agents. J Med Chem37:2552-63 (1994) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| D(2) dopamine receptor |
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| Name: | D(2) dopamine receptor |
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| Synonyms: | DOPAMINE D2 | DOPAMINE D2 Long | DOPAMINE D2 Short | DRD2_RAT | Dopamine D2 receptor | Dopamine2-like | Drd2 |
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| Type: | G Protein-Coupled Receptor (GPCR) |
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| Mol. Mass.: | 50931.60 |
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| Organism: | Rattus norvegicus (rat) |
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| Description: | P61169 |
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| Residue: | 444 |
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| Sequence: | MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVS
REKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTA
SILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQN
ECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPL
KGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPP
SHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMS
RRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNS
AVNPIIYTTFNIEFRKAFMKILHC
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| BDBM50036927 |
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| n/a |
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| Name | BDBM50036927 |
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| Synonyms: | 2-[4-(4-Benzo[d]isothiazol-3-yl-piperazin-1-yl)-butyl]-2,3,4,5-tetrahydro-benzo[c]azepin-1-one | CHEMBL315925 |
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| Type | Small organic molecule |
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| Emp. Form. | C25H30N4OS |
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| Mol. Mass. | 434.597 |
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| SMILES | O=C1N(CCCCN2CCN(CC2)c2nsc3ccccc23)CCCc2ccccc12 |
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| Structure | 
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