| Reaction Details |
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 | Report a problem with these data |
| Target | Neuropeptide FF receptor 2 |
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| Ligand | BDBM50037576 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_143663 (CHEMBL755904) |
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| Ki | 0.6±n/a nM |
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| Citation |  Gicquel, S; Mazarguil, H; Desprat, C; Allard, M; Devillers, JP; Simonnet, G; Zajac, JM Structure-activity study of neuropeptide FF: contribution of N-terminal regions to affinity and activity. J Med Chem37:3477-81 (1994) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| Neuropeptide FF receptor 2 |
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| Name: | Neuropeptide FF receptor 2 |
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| Synonyms: | G-protein coupled receptor 74 | Gpr74 | NPFF2_RAT | Neuropeptide G-protein coupled receptor | Npff2 | Npffr2 | Npgpr |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 47725.66 |
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| Organism: | RAT |
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| Description: | NPFF2 0 RAT::Q9EQD2 |
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| Residue: | 417 |
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| Sequence: | MGKRWDSNSSGSWDHIWSGNDTQHPWYSDINITYMNYYLHQPHVTAVFISSYFLIFFLCM
VGNTVVCFVVIRNRYMHTVTNFFIFNLAISDLLVGIFCMPITLLDNIIAGWPFGSSMCKI
SGLVQGISVAASVFTLVAIAVDRFRCVVYPFKPKLTVKTAFVMIVIIWGLAITIMTPSAI
MLHVQEEKYYRVRLSSHNKTSTVYWCREDWPNQEMRRIYTTVLFATIYLAPLSLIVIMYA
RIGASLFKTSAHSTGKQRLEQWHVSKKKQKVIKMLLTVALLFILSWLPLWTLMMLSDYAD
LSPNKLRVINIYVYPFAHWLAFCNSSVNPIIYGFFNENFRSGFQDAFQFCQKKVKPQEAY
GLRAKRNLDINTSGLLVHEPASQNPSGENLGCRKSADNPTQESLMEETGEATNSTET
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| BDBM50037576 |
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| n/a |
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| Name | BDBM50037576 |
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| Synonyms: | 1-(2-{2-[2-(2-Amino-3-phenyl-propionylamino)-4-methyl-pentanoylamino]-3-phenyl-propionylamino}-4-carbamoyl-butyryl)-pyrrolidine-2-carboxylic acid {[1-(1-carbamoyl-2-phenyl-ethylcarbamoyl)-4-guanidino-butylcarbamoyl]-methyl}-amide | CHEMBL266976 |
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| Type | Small organic molecule |
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| Emp. Form. | C51H71N13O9 |
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| Mol. Mass. | 1010.1911 |
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| SMILES | CC(C)C[C@H](NC(=O)[C@@H](N)Cc1ccccc1)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCC(N)=O)C(=O)N1CCC[C@H]1C(=O)NCC(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1ccccc1)C(N)=O |
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| Structure | 
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