| Reaction Details |
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 | Report a problem with these data |
| Target | Glutamate receptor ionotropic, NMDA 2C |
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| Ligand | BDBM50038162 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_140463 (CHEMBL884513) |
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| EC50 | 400±n/a nM |
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| Citation |  Leeson, PD; Iversen, LL The glycine site on the NMDA receptor: structure-activity relationships and therapeutic potential. J Med Chem37:4053-67 (1995) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| Glutamate receptor ionotropic, NMDA 2C |
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| Name: | Glutamate receptor ionotropic, NMDA 2C |
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| Synonyms: | Glutamate NMDA receptor; Grin1/Grin2c | Glutamate receptor ionotropic, NMDA 2C | Grin2c | NMDA receptor subunit 2C (GluN2C) | NMDE3_RAT |
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| Type: | Protein |
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| Mol. Mass.: | 135305.94 |
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| Organism: | Rattus norvegicus (Rat) |
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| Description: | Q00961 |
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| Residue: | 1237 |
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| Sequence: | MGGALGPALLLTSLLGAWARLGAGQGEQAVTVAVVFGSSGPLQTQARTRLTSQNFLDLPL
EIQPLTVGVNNTNPSSILTQICGLLGAARVHGIVFEDNVDTEAVAQLLDFVSSQTHVPIL
SISGGSAVVLTPKEPGSAFLQLGVSLEQQLQVLFKVLEEYDWSAFAVITSLHPGHALFLE
GVRAVADASYLSWRLLDVLTLELGPGGPRARTQRLLRQVDAPVLVAYCSREEAEVLFAEA
AQAGLVGPGHVWLVPNLALGSTDAPPAAFPVGLISVVTESWRLSLRQKVRDGVAILALGA
HSYRRQYGTLPAPAGDCRSHPGPVSPAREAFYRHLLNVTWEGRDFSFSPGGYLVRPTMVV
IALNRHRLWEMVGRWDHGVLYMKYPVWPRYSTSLQPVVDSRHLTVATLEERPFVIVESPD
PGTGGCVPNTVPCRRQSNHTFSSGDLTPYTKLCCKGFCIDILKKLAKVVKFSYDLYLVTN
GKHGKRVRGVWNGMIGEVYYKRADMAIGSLTINEERSEIIDFSVPFVETGISVMVSRSNG
TVSPSAFLEPYSPAVWVMMFVMCLTVVAITVFMFEYFSPVSYNQNLTKGKKPGGPSFTIG
KSVWLLWALVFNNSVPIENPRGTTSKIMVLVWAFFAVIFLASYTANLAAFMIQEQYIDTV
SGLSDKKFQRPQDQYPPFRFGTVPNGSTERNIRSNYRDMHTHMVKFNQRSVEDALTSLKM
GKLDAFIYDAAVLNYMAGKDEGCKLVTIGSGKVFATTGYGIAMQKDSHWKRAIDLALLQL
LGDGETQKLETVWLSGICQNEKNEVMSSKLDIDNMAGVFYMLLVAMGLALLVFAWEHLVY
WKLRHSVPNSSQLDFLLAFSRGIYSCFNGVQSLPSPARPPSPDLTADSAQANVLKMLQAA
RDMVNTADVSSSLDRATRTIENWGNNRRVPAPTASGPRSSTPGPPGQPSPSGWGPPGGGR
TPLARRAPQPPARPATCGPPLPDVSRPSCRHASDARWPVRVGHQGPHVSASERRALPERS
LLPAHCHYSSFPRAERSGRPYLPLFPEPPEPDDLPLLGPEQLARREAMLRAAWARGPRPR
HASLPSSVAEAFTRSNPLPARCTGHACACPCPQSRPSCRHLAQAQSLRLPSYPEACVEGV
PAGVATWQPRQHVCLHAHTRLPFCWGTVCRHPPPCTSHSPWLIGTWEPPAHRVRTLGLGT
GYRDSGVLEEVSREACGTQGFPRSCTWRRVSSLESEV
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| BDBM50038162 |
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| n/a |
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| Name | BDBM50038162 |
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| Synonyms: | 5,7-Dinitro-1,4-dihydro-quinoxaline-2,3-dione | CHEMBL323335 |
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| Type | Small organic molecule |
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| Emp. Form. | C8H4N4O6 |
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| Mol. Mass. | 252.1406 |
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| SMILES | [O-][N+](=O)c1cc([N+]([O-])=O)c2[nH]c(=O)c(=[OH+])[n-]c2c1 |
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| Structure | 
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