| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Alpha-2A adrenergic receptor |
|---|
| Ligand | BDBM50417344 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_986496 (CHEMBL2434577) |
|---|
| Ki | 23±n/a nM |
|---|
| Citation |  Del Bello, F; Diamanti, E; Giannella, M; Mammoli, V; Mattioli, L; Titomanlio, F; Piergentili, A; Quaglia, W; Lanza, M; Sabatini, C; Caselli, G; Poggesi, E; Pigini, M Exploring multitarget interactions to reduce opiate withdrawal syndrome and psychiatric comorbidity. ACS Med Chem Lett4:875-9 (2013) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Alpha-2A adrenergic receptor |
|---|
| Name: | Alpha-2A adrenergic receptor |
|---|
| Synonyms: | ADA2A_HUMAN | ADRA2A | ADRA2R | ADRAR | Adrenergic alpha2A | Adrenergic receptor alpha | Alpha-2 adrenergic receptor subtype C10 | Alpha-2A adrenoceptor | Alpha-2A adrenoreceptor | Alpha-2AAR | alpha-2A adrenergic receptor [Homo sapiens] |
|---|
| Type: | Enzyme |
|---|
| Mol. Mass.: | 48979.91 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | P08913 |
|---|
| Residue: | 465 |
|---|
| Sequence: | MFRQEQPLAEGSFAPMGSLQPDAGNASWNGTEAPGGGARATPYSLQVTLTLVCLAGLLML
LTVFGNVLVIIAVFTSRALKAPQNLFLVSLASADILVATLVIPFSLANEVMGYWYFGKAW
CEIYLALDVLFCTSSIVHLCAISLDRYWSITQAIEYNLKRTPRRIKAIIITVWVISAVIS
FPPLISIEKKGGGGGPQPAEPRCEINDQKWYVISSCIGSFFAPCLIMILVYVRIYQIAKR
RTRVPPSRRGPDAVAAPPGGTERRPNGLGPERSAGPGGAEAEPLPTQLNGAPGEPAPAGP
RDTDALDLEESSSSDHAERPPGPRRPERGPRGKGKARASQVKPGDSLPRRGPGATGIGTP
AAGPGEERVGAAKASRWRGRQNREKRFTFVLAVVIGVFVVCWFPFFFTYTLTAVGCSVPR
TLFKFFFWFGYCNSSLNPVIYTIFNHDFRRAFKKILCRGDRKRIV
|
|
|
|---|
| BDBM50417344 |
|---|
| n/a |
|---|
| Name | BDBM50417344 |
|---|
| Synonyms: | CHEMBL1276218 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C14H18N2O |
|---|
| Mol. Mass. | 230.3055 |
|---|
| SMILES | CC(Oc1ccccc1C1CC1)C1=NCCN1 |t:14| |
|---|
| Structure | 
|
|---|
Search and Browse
