| Reaction Details |
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 | Report a problem with these data |
| Target | Adenosine receptor A1 |
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| Ligand | BDBM50039677 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_29595 (CHEMBL640253) |
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| IC50 | 800±n/a nM |
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| Citation |  Scammells, PJ; Baker, SP; Belardinelli, L; Olsson, RA Substituted 1,3-dipropylxanthines as irreversible antagonists of A1 adenosine receptors. J Med Chem37:2704-12 (1994) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| Adenosine receptor A1 |
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| Name: | Adenosine receptor A1 |
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| Synonyms: | A1 adenosine receptor (hA1) | A1AR | AA1R_HUMAN | ADENOSINE A1 | ADORA1 | Adenosine A1 receptor (A1AR) | Adenosine A1-receptor | Adenosine receptor A1 (A1) | Adenosine receptor A1 (hA1) | Adenosine transporter (AdT) |
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| Type: | G Protein-Coupled Receptor (GPCR) |
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| Mol. Mass.: | 36520.92 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P30542 |
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| Residue: | 326 |
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| Sequence: | MPPSISAFQAAYIGIEVLIALVSVPGNVLVIWAVKVNQALRDATFCFIVSLAVADVAVGA
LVIPLAILINIGPQTYFHTCLMVACPVLILTQSSILALLAIAVDRYLRVKIPLRYKMVVT
PRRAAVAIAGCWILSFVVGLTPMFGWNNLSAVERAWAANGSMGEPVIKCEFEKVISMEYM
VYFNFFVWVLPPLLLMVLIYLEVFYLIRKQLNKKVSASSGDPQKYYGKELKIAKSLALIL
FLFALSWLPLHILNCITLFCPSCHKPSILTYIAIFLTHGNSAMNPIVYAFRIQKFRVTFL
KIWNDHFRCQPAPPIDEDLPEERPDD
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| BDBM50039677 |
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| n/a |
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| Name | BDBM50039677 |
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| Synonyms: | 4-[3-(2,6-Dioxo-1,3-dipropyl-2,3,6,7-tetrahydro-1H-purin-8-yl)-propylcarbamoyl]-benzenesulfonyl fluoride | CHEMBL89920 |
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| Type | Small organic molecule |
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| Emp. Form. | C21H26FN5O5S |
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| Mol. Mass. | 479.525 |
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| SMILES | CCCn1c2nc(CCCNC(=O)c3ccc(cc3)S(F)(=O)=O)[nH]c2c(=O)n(CCC)c1=O |
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| Structure | 
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