| Reaction Details |
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 | Report a problem with these data |
| Target | Reverse transcriptase |
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| Ligand | BDBM50493796 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_989557 (CHEMBL2444613) |
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| IC50 | 72±n/a nM |
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| Citation |  Wu, HQ; Yan, ZH; Chen, WX; He, QQ; Chen, FE; De Clercq, E; Balzarini, J; Daelemans, D; Pannecouque, C Towards new C6-rigid S-DABO HIV-1 reverse transcriptase inhibitors: synthesis, biological investigation and molecular modeling studies. Bioorg Med Chem21:6477-83 (2013) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Reverse transcriptase |
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| Name: | Reverse transcriptase |
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| Synonyms: | n/a |
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| Type: | Protein |
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| Mol. Mass.: | 29598.37 |
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| Organism: | Human immunodeficiency virus 1 |
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| Description: | Q9WKE8 |
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| Residue: | 254 |
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| Sequence: | PISPITVPVKLKPGMDGPKVKQWPLTEEKIKALTEICTEMEKEGKIEKIGPENPYNTPVF
AIKKKDSTKWRKVVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPLD
KDFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRKQNPDIVIY
QYMDDLYVGSDLEIEQHRAKIEELRQHLLRWGFTTPDKKHQKEPPFLWMGYELHPDKWTV
QPIVLPEKDSWTVN
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| BDBM50493796 |
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| n/a |
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| Name | BDBM50493796 |
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| Synonyms: | CHEMBL2443100 |
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| Type | Small organic molecule |
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| Emp. Form. | C22H21FN2O3S |
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| Mol. Mass. | 412.477 |
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| SMILES | COc1ccc(CSc2nc(C(=O)c3ccccc3F)c(C(C)C)c(=O)[nH]2)cc1 |
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| Structure | 
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