| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Carbonic anhydrase 7 |
|---|
| Ligand | BDBM50380149 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_989827 (CHEMBL2446503) |
|---|
| Kd | 100±n/a nM |
|---|
| Citation |  ?apkauskait?, E; Zubrien?, A; Smirnov, A; Torresan, J; Ki?onait?, M; Kazokait?, J; Gylyt?, J; Michailovien?, V; Jogait?, V; Manakova, E; Gra?ulis, S; Tumkevi?ius, S; Matulis, D Benzenesulfonamides with pyrimidine moiety as inhibitors of human carbonic anhydrases I, II, VI, VII, XII, and XIII. Bioorg Med Chem21:6937-47 (2013) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Carbonic anhydrase 7 |
|---|
| Name: | Carbonic anhydrase 7 |
|---|
| Synonyms: | CA-VII | CA7 | CAH7_HUMAN | Carbonate dehydratase VII | Carbonic anhydrase | Carbonic anhydrase VII | Carbonic anhydrase VII (CA VII) |
|---|
| Type: | Enzyme |
|---|
| Mol. Mass.: | 29664.11 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | Human cloned isozyme. |
|---|
| Residue: | 264 |
|---|
| Sequence: | MTGHHGWGYGQDDGPSHWHKLYPIAQGDRQSPINIISSQAVYSPSLQPLELSYEACMSLS
ITNNGHSVQVDFNDSDDRTVVTGGPLEGPYRLKQFHFHWGKKHDVGSEHTVDGKSFPSEL
HLVHWNAKKYSTFGEAASAPDGLAVVGVFLETGDEHPSMNRLTDALYMVRFKGTKAQFSC
FNPKCLLPASRHYWTYPGSLTTPPLSESVTWIVLREPICISERQMGKFRSLLFTSEDDER
IHMVNNFRPPQPLKGRVVKASFRA
|
|
|
|---|
| BDBM50380149 |
|---|
| n/a |
|---|
| Name | BDBM50380149 |
|---|
| Synonyms: | CHEMBL2011154 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C16H19N3O3S2 |
|---|
| Mol. Mass. | 365.47 |
|---|
| SMILES | CCCCc1cnc(SCC(=O)c2ccc(cc2)S(N)(=O)=O)nc1 |
|---|
| Structure | 
|
|---|
Search and Browse
