| Reaction Details |
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 | Report a problem with these data |
| Target | E-selectin |
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| Ligand | BDBM50029637 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_60885 (CHEMBL673532) |
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| IC50 | 3300±n/a nM |
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| Citation |  Boschelli, DH; Kramer, JB; Connor, DT; Lesch, ME; Schrier, DJ; Ferin, MA; Wright, CD 3-Alkoxybenzo[b]thiophene-2-carboxamides as inhibitors of neutrophil-endothelial cell adhesion. J Med Chem37:717-8 (1994) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| |
| E-selectin |
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| Name: | E-selectin |
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| Synonyms: | ELAM1 | LYAM2_HUMAN | SELE | Selectin | Selectin E |
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| Type: | PROTEIN |
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| Mol. Mass.: | 66642.96 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_1438995 |
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| Residue: | 610 |
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| Sequence: | MIASQFLSALTLVLLIKESGAWSYNTSTEAMTYDEASAYCQQRYTHLVAIQNKEEIEYLN
SILSYSPSYYWIGIRKVNNVWVWVGTQKPLTEEAKNWAPGEPNNRQKDEDCVEIYIKREK
DVGMWNDERCSKKKLALCYTAACTNTSCSGHGECVETINNYTCKCDPGFSGLKCEQIVNC
TALESPEHGSLVCSHPLGNFSYNSSCSISCDRGYLPSSMETMQCMSSGEWSAPIPACNVV
ECDAVTNPANGFVECFQNPGSFPWNTTCTFDCEEGFELMGAQSLQCTSSGNWDNEKPTCK
AVTCRAVRQPQNGSVRCSHSPAGEFTFKSSCNFTCEEGFMLQGPAQVECTTQGQWTQQIP
VCEAFQCTALSNPERGYMNCLPSASGSFRYGSSCEFSCEQGFVLKGSKRLQCGPTGEWDN
EKPTCEAVRCDAVHQPPKGLVRCAHSPIGEFTYKSSCAFSCEEGFELHGSTQLECTSQGQ
WTEEVPSCQVVKCSSLAVPGKINMSCSGEPVFGTVCKFACPEGWTLNGSAARTCGATGHW
SGLLPTCEAPTESNIPLVAGLSAAGLSLLTLAPFLLWLRKCLRKAKKFVPASSCQSLESD
GSYQKPSYIL
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| BDBM50029637 |
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| n/a |
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| Name | BDBM50029637 |
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| Synonyms: | 5-Hydroxy-3-isopropoxy-benzo[b]thiophene-2-carboxylic acid amide | CHEMBL336269 |
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| Type | Small organic molecule |
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| Emp. Form. | C12H13NO3S |
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| Mol. Mass. | 251.302 |
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| SMILES | CC(C)Oc1c(sc2ccc(O)cc12)C(N)=O |
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| Structure | 
|
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