Reaction Details |
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Target | Sigma non-opioid intracellular receptor 1 |
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Ligand | BDBM50007410 |
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Substrate/Competitor | n/a |
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Meas. Tech. | ChEMBL_1280662 (CHEMBL3097103) |
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Ki | 0.120000±n/a nM |
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Citation | Motel, WC; Healy, JR; Viard, E; Pouw, B; Martin, K; Matsumoto, RR; Coop, A Chlorophenylpiperazine analogues as high affinity dopamine transporter ligands. Bioorg Med Chem Lett23:6920-6922 (2013) [PubMed] Article |
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More Info.: | Get all data from this article, Assay Method |
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Sigma non-opioid intracellular receptor 1 |
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Name: | Sigma non-opioid intracellular receptor 1 |
Synonyms: | Opioid receptor | Oprs1 | SGMR1_RAT | Sigma | Sigma non-opioid intracellular receptor 1 | Sigma opioid receptor | Sigma-1 | Sigmar1 |
Type: | Enzyme Catalytic Domain |
Mol. Mass.: | 25266.54 |
Organism: | RAT |
Description: | Q9R0C9 |
Residue: | 223 |
Sequence: | MPWAVGRRWAWITLFLTIVAVLIQAVWLWLGTQSFVFQREEIAQLARQYAGLDHELAFSR
LIVELRRLHPGHVLPDEELQWVFVNAGGWMGAMCLLHASLSEYVLLFGTALGSHGHSGRY
WAEISDTIISGTFHQWREGTTKSEVYYPGETVVHGPGEATAVEWGPNTWMVEYGRGVIPS
TLAFALSDTIFSTQDFLTLFYTLRAYARGLRLELTTYLFGQDP
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BDBM50007410 |
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n/a |
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Name | BDBM50007410 |
Synonyms: | 1-(4-Chloro-phenyl)-4-(3-phenyl-propyl)-piperazine | CHEMBL112125 |
Type | Small organic molecule |
Emp. Form. | C19H23ClN2 |
Mol. Mass. | 314.852 |
SMILES | Clc1ccc(cc1)N1CCN(CCCc2ccccc2)CC1 |
Structure |
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