| Reaction Details |
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 | Report a problem with these data |
| Target | Carbonic anhydrase 7 |
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| Ligand | BDBM10857 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1282512 (CHEMBL3101065) |
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| Ki | 70±n/a nM |
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| Citation |  Bozdag, M; Ferraroni, M; Nuti, E; Vullo, D; Rossello, A; Carta, F; Scozzafava, A; Supuran, CT Combining the tail and the ring approaches for obtaining potent and isoform-selective carbonic anhydrase inhibitors: solution and X-ray crystallographic studies. Bioorg Med Chem22:334-40 (2014) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Carbonic anhydrase 7 |
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| Name: | Carbonic anhydrase 7 |
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| Synonyms: | CA-VII | CA7 | CAH7_HUMAN | Carbonate dehydratase VII | Carbonic anhydrase | Carbonic anhydrase VII | Carbonic anhydrase VII (CA VII) |
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| Type: | Enzyme |
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| Mol. Mass.: | 29664.11 |
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| Organism: | Homo sapiens (Human) |
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| Description: | Human cloned isozyme. |
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| Residue: | 264 |
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| Sequence: | MTGHHGWGYGQDDGPSHWHKLYPIAQGDRQSPINIISSQAVYSPSLQPLELSYEACMSLS
ITNNGHSVQVDFNDSDDRTVVTGGPLEGPYRLKQFHFHWGKKHDVGSEHTVDGKSFPSEL
HLVHWNAKKYSTFGEAASAPDGLAVVGVFLETGDEHPSMNRLTDALYMVRFKGTKAQFSC
FNPKCLLPASRHYWTYPGSLTTPPLSESVTWIVLREPICISERQMGKFRSLLFTSEDDER
IHMVNNFRPPQPLKGRVVKASFRA
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| BDBM10857 |
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| n/a |
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| Name | BDBM10857 |
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| Synonyms: | 4-aminobenzene-1-sulfonamide | CHEMBL21 | Sulfanilamide | aromatic sulfonamide compound 5 | aromatic/heteroaromatic sulfonamide 2 | halogenosulfanilamide deriv. 5a |
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| Type | Small organic molecule |
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| Emp. Form. | C6H8N2O2S |
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| Mol. Mass. | 172.205 |
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| SMILES | Nc1ccc(cc1)S(N)(=O)=O |
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| Structure | 
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