| Reaction Details |
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 | Report a problem with these data |
| Target | D(2) dopamine receptor |
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| Ligand | BDBM50041959 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_59485 (CHEMBL670137) |
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| Ki | 158±n/a nM |
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| Citation |  Sonesson, C; Waters, N; Svensson, K; Carlsson, A; Smith, MW; Piercey, MF; Meier, E; Wikström, H Substituted 3-phenylpiperidines: new centrally acting dopamine autoreceptor antagonists. J Med Chem36:3188-96 (1993) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| D(2) dopamine receptor |
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| Name: | D(2) dopamine receptor |
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| Synonyms: | DOPAMINE D2 | DRD2 | DRD2_BOVIN | Dopamine D2 receptor |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 50698.79 |
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| Organism: | BOVINE |
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| Description: | P20288 |
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| Residue: | 444 |
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| Sequence: | MDPLNLSWYDDDPESRNWSRPFNGSEGKADRPPYNYYAMLLTLLIFVIVFGNVLVCMAVS
REKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTA
SILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPMLFGLNNTDQN
ECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRANLKAPL
KGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPP
SHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKTVNPKIAKIFEIQSMPNGKTRTSLKTMS
RRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNS
AVNPIIYTTFNIEFRKAFLKILHC
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| BDBM50041959 |
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| n/a |
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| Name | BDBM50041959 |
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| Synonyms: | ((1S,2R)-5-Methoxy-1-methyl-1,2,3,4-tetrahydro-naphthalen-2-yl)-propyl-amine | (+)-(5-Methoxy-1-methyl-1,2,3,4-tetrahydro-naphthalen-2-yl)-propyl-amine | (1S,2R)-(5-Methoxy-1-methyl-1,2,3,4-tetrahydro-naphthalen-2-yl)-propyl-amine | (5-Methoxy-1-methyl-1,2,3,4-tetrahydro-naphthalen-2-yl)-propyl-amine | AJ76(+) | CHEMBL27441 |
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| Type | Small organic molecule |
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| Emp. Form. | C15H23NO |
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| Mol. Mass. | 233.3492 |
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| SMILES | CCCN[C@@H]1CCc2c(OC)cccc2[C@@H]1C |
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| Structure | 
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