| Reaction Details |
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 | Report a problem with these data |
| Target | Adenosine receptor A1 |
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| Ligand | BDBM50014260 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEBML_29009 |
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| Ki | 105000±n/a nM |
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| Citation |  Müller, CE; Shi, D; Manning, M; Daly, JW Synthesis of paraxanthine analogs (1,7-disubstituted xanthines) and other xanthines unsubstituted at the 3-position: structure-activity relationships at adenosine receptors. J Med Chem36:3341-9 (1993) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| Adenosine receptor A1 |
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| Name: | Adenosine receptor A1 |
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| Synonyms: | AA1R_RAT | ADENOSINE A1 | ADENOSINE A1 high | ADENOSINE A1 low | Adenosine A1 receptor (A1) | Adenosine receptor | Adenosine receptors A1 | Adora1 |
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| Type: | Protein |
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| Mol. Mass.: | 36704.13 |
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| Organism: | Rattus norvegicus (rat) |
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| Description: | n/a |
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| Residue: | 326 |
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| Sequence: | MPPYISAFQAAYIGIEVLIALVSVPGNVLVIWAVKVNQALRDATFCFIVSLAVADVAVGA
LVIPLAILINIGPQTYFHTCLMVACPVLILTQSSILALLAIAVDRYLRVKIPLRYKTVVT
QRRAAVAIAGCWILSLVVGLTPMFGWNNLSVVEQDWRANGSVGEPVIKCEFEKVISMEYM
VYFNFFVWVLPPLLLMVLIYLEVFYLIRKQLNKKVSASSGDPQKYYGKELKIAKSLALIL
FLFALSWLPLHILNCITLFCPTCQKPSILIYIAIFLTHGNSAMNPIVYAFRIHKFRVTFL
KIWNDHFRCQPKPPIDEDLPEEKAED
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| BDBM50014260 |
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| n/a |
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| Name | BDBM50014260 |
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| Synonyms: | 3,7-dihydro-3,7-dimethyl-1H-purine-2,6-dione | 3,7-dimethyl-3,7-dihydro-1H-purine-2,6-dione | 3,7-dimethylpurine-2,6-dione | 3,7-dimethylxanthine | CHEMBL1114 | Theobromin | theobromine |
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| Type | Small organic molecule |
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| Emp. Form. | C7H8N4O2 |
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| Mol. Mass. | 180.164 |
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| SMILES | Cn1cnc2n(C)c(=O)[nH]c(=O)c12 |
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| Structure | 
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