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| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | Type-1 angiotensin II receptor B | ||
| Ligand | BDBM50042228 | ||
| Substrate/Competitor | n/a | ||
| Meas. Tech. | ChEBML_34806 | ||
| IC50 | 66±n/a nM | ||
| Citation |  Bernhart, CA; Perreaut, PM; Ferrari, BP; Muneaux, YA; Assens, JL; Clément, J; Haudricourt, F; Muneaux, CF; Taillades, JE; Vignal, MA A new series of imidazolones: highly specific and potent nonpeptide AT1 angiotensin II receptor antagonists. J Med Chem36:3371-80 (1993) [PubMed] | ||
| More Info.: | Get all data from this article, Assay Method | ||
| Type-1 angiotensin II receptor B | |||
| Name: | Type-1 angiotensin II receptor B | ||
| Synonyms: | AGTRB_RAT | AT3 | Agtr1 | Agtr1b | Angiotensin II AT1B | Angiotensin II receptor (AT-1) type-1 | Angiotensin II type 1b (AT-1b) receptor | At1b | Type-1B angiotensin II receptor | ||
| Type: | Enzyme Catalytic Domain | ||
| Mol. Mass.: | 40929.44 | ||
| Organism: | RAT | ||
| Description: | Angiotensin II AT1B 0 RAT::P29089 | ||
| Residue: | 359 | ||
| Sequence: |
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| BDBM50042228 | |||
| n/a | |||
| Name | BDBM50042228 | ||
| Synonyms: | 4'-(2-Butyl-8-methyl-4-oxo-1,3-diaza-spiro[4.5]dec-1-en-3-ylmethyl)-biphenyl-2-carboxylic acid | CHEMBL114656 | ||
| Type | Small organic molecule | ||
| Emp. Form. | C27H32N2O3 | ||
| Mol. Mass. | 432.5546 | ||
| SMILES | CCCCC1=NC2(CCC(C)CC2)C(=O)N1Cc1ccc(cc1)-c1ccccc1C(O)=O |t:4,(3.07,-11.48,;4.4,-10.72,;4.4,-9.18,;5.71,-8.41,;5.74,-6.86,;4.47,-5.97,;4.95,-4.5,;3.44,-4.66,;2.55,-3.42,;3.17,-2.02,;2.27,-.78,;4.69,-1.86,;5.59,-3.1,;6.5,-4.49,;7.4,-3.25,;6.98,-5.97,;8.06,-7.04,;9.6,-7.04,;10.36,-5.7,;11.88,-5.7,;12.66,-7.04,;11.9,-8.38,;10.36,-8.38,;14.21,-7.04,;14.95,-5.7,;16.5,-5.68,;17.28,-7.02,;16.52,-8.36,;14.98,-8.36,;14.21,-9.72,;12.66,-9.72,;14.98,-11.04,)| | ||
| Structure | 
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