| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Papain |
|---|
| Ligand | BDBM50042415 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEBML_152654 |
|---|
| pH | 6±n/a |
|---|
| Ki | 93000±n/a nM |
|---|
| Comments | extracted |
|---|
| Citation |  Li, Z; Patil, GS; Golubski, ZE; Hori, H; Tehrani, K; Foreman, JE; Eveleth, DD; Bartus, RT; Powers, JC Peptide alpha-keto ester, alpha-keto amide, and alpha-keto acid inhibitors of calpains and other cysteine proteases. J Med Chem36:3472-80 (1993) [PubMed] |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Papain |
|---|
| Name: | Papain |
|---|
| Synonyms: | Allergen=Car p 1 | PAPA1_CARPA | PPI | Papaya proteinase I |
|---|
| Type: | Enzyme |
|---|
| Mol. Mass.: | 38923.01 |
|---|
| Organism: | Carica papaya |
|---|
| Description: | Papain was purchased from Sigma, Germany. |
|---|
| Residue: | 345 |
|---|
| Sequence: | MAMIPSISKLLFVAICLFVYMGLSFGDFSIVGYSQNDLTSTERLIQLFESWMLKHNKIYK
NIDEKIYRFEIFKDNLKYIDETNKKNNSYWLGLNVFADMSNDEFKEKYTGSIAGNYTTTE
LSYEEVLNDGDVNIPEYVDWRQKGAVTPVKNQGSCGSCWAFSAVVTIEGIIKIRTGNLNE
YSEQELLDCDRRSYGCNGGYPWSALQLVAQYGIHYRNTYPYEGVQRYCRSREKGPYAAKT
DGVRQVQPYNEGALLYSIANQPVSVVLEAAGKDFQLYRGGIFVGPCGNKVDHAVAAVGYG
PNYILIKNSWGTGWGENGYIRIKRGTGNSYGVCGLYTSSFYPVKN
|
|
|
|---|
| BDBM50042415 |
|---|
| n/a |
|---|
| Name | BDBM50042415 |
|---|
| Synonyms: | CHEMBL444594 | [1-(1-Butylaminooxalyl-propylcarbamoyl)-3-methyl-butyl]-carbamic acid benzyl ester |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C23H35N3O5 |
|---|
| Mol. Mass. | 433.5411 |
|---|
| SMILES | CCCCNC(=O)C(=O)C(CC)NC(=O)C(CC(C)C)NC(=O)OCc1ccccc1 |
|---|
| Structure | 
|
|---|
Search and Browse
