Reaction Details |
| Report a problem with these data |
Target | Trace amine-associated receptor 1 |
---|
Ligand | BDBM10758 |
---|
Substrate/Competitor | n/a |
---|
Meas. Tech. | ChEMBL_1287612 (CHEMBL3110494) |
---|
EC50 | 40±n/a nM |
---|
Citation | Reese, EA; Norimatsu, Y; Grandy, MS; Suchland, KL; Bunzow, JR; Grandy, DK Exploring the determinants of trace amine-associated receptor 1's functional selectivity for the stereoisomers of amphetamine and methamphetamine. J Med Chem57:378-90 (2014) [PubMed] Article |
---|
More Info.: | Get all data from this article, Assay Method |
---|
|
Trace amine-associated receptor 1 |
---|
Name: | Trace amine-associated receptor 1 |
Synonyms: | TAAR1_RAT | Ta1 | Taar1 | Tar1 | Trace amine receptor 1 (TARR1) | Trace amine-associated receptor 1 | Trace amine-associated receptor 1 (TAAR1) | Trace amine-associated receptor1 | Trar1 |
Type: | Enzyme |
Mol. Mass.: | 38034.73 |
Organism: | Rattus norvegicus (Rat) |
Description: | Q923Y9 |
Residue: | 332 |
Sequence: | MHLCHNSANISHTNSNWSRDVRASLYSLISLIILTTLVGNLIVIISISHFKQLHTPTNWL
LHSMAVVDFLLGCLVMPYSMVRTVEHCWYFGELFCKLHTSTDIMLSSASILHLAFISIDR
YYAVCDPLRYKAKINLAAIFVMILISWSLPAVFAFGMIFLELNLEGVEELYHNQVFCLRG
CFPFFSKVSGVLAFMTSFYIPGSVMLFVYYRIYFIAKGQARSINRANLQVGLEGESRAPQ
SKETKAAKTLGIMVGVFLLCWCPFFFCMVLDPFLGYVIPPTLNDTLNWFGYLNSAFNPMV
YAFFYPWFRRALKMVLFGKIFQKDSSRSKLFL
|
|
|
BDBM10758 |
---|
n/a |
---|
Name | BDBM10758 |
Synonyms: | 14C-phenylethylamine | 2-phenylethan-1-amine | CHEMBL610 | phenylethylamine |
Type | Small organic molecule |
Emp. Form. | C8H11N |
Mol. Mass. | 121.1796 |
SMILES | NCCc1ccccc1 |
Structure |
|