| Reaction Details |
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 | Report a problem with these data |
| Target | Thyrotropin-releasing hormone receptor |
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| Ligand | BDBM85330 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEBML_207481 |
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| Ki | >10000±n/a nM |
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| Citation |  van Wijngaarden, I; Hamminga, D; van Hes, R; Standaar, PJ; Tipker, J; Tulp, MT; Mol, F; Olivier, B; de Jonge, A Development of high-affinity 5-HT3 receptor antagonists. Structure-affinity relationships of novel 1,7-annelated indole derivatives. J Med Chem36:3693-9 (1994) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| Thyrotropin-releasing hormone receptor |
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| Name: | Thyrotropin-releasing hormone receptor |
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| Synonyms: | TRH-R | TRHR_RAT | Thyroliberin receptor | Trhr |
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| Type: | PROTEIN |
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| Mol. Mass.: | 46618.79 |
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| Organism: | Rattus norvegicus |
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| Description: | ChEMBL_303571 |
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| Residue: | 412 |
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| Sequence: | MENETVSELNQTELPPQVAVALEYQVVTILLVVVICGLGIVGNIMVVLVVMRTKHMRTAT
NCYLVSLAVADLMVLVAAGLPNITDSIYGSWVYGYVGCLCITYLQYLGINASSCSITAFT
IERYIAICHPIKAQFLCTFSRAKKIIIFVWAFTSIYCMLWFFLLDLNISTYKDAIVISCG
YKISRNYYSPIYLMDFGVFYVMPMILATVLYGFIARILFLNPIPSDPKENSKTWKNDSTH
QNKNMNLNTTNRCFNSTVSSRKQVTKMLAVVVILFALLWMPYRTLVVVNSFLSSPFQENW
FLLFCRICIYLNSAINPVIYNLMSQKFRAAFRKLCNCKQKPTEKAANYSVALNYSVIKES
DRFSTELDDITVTDTYVSTTKVSFDDTCLASEKNGPSSCTYGYSLTAKQEKI
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| BDBM85330 |
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| n/a |
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| Name | BDBM85330 |
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| Synonyms: | CAS_68647 | NSC_68647 | ONDANSETRON | Ondansetron hydrochloride |
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| Type | Small organic molecule |
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| Emp. Form. | C18H19N3O |
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| Mol. Mass. | 293.363 |
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| SMILES | Cc1nccn1CC1CCc2c(C1=O)c1ccccc1n2C |
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| Structure | 
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