Search and Browse
Download
Enter Data
| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | Cannabinoid receptor 2 | ||
| Ligand | BDBM50495627 | ||
| Substrate/Competitor | n/a | ||
| Meas. Tech. | ChEMBL_1291676 (CHEMBL3119423) | ||
| Ki | 53±n/a nM | ||
| Citation |  Lucchesi, V; Parkkari, T; Savinainen, JR; Malfitano, AM; Allarà, M; Bertini, S; Castelli, F; Del Carlo, S; Laezza, C; Ligresti, A; Saccomanni, G; Bifulco, M; Di Marzo, V; Macchia, M; Manera, C 1,2-Dihydro-2-oxopyridine-3-carboxamides: the C-5 substituent is responsible for functionality switch at CB2 cannabinoid receptor. Eur J Med Chem74:524-32 (2014) [PubMed] Article | ||
| More Info.: | Get all data from this article, Assay Method | ||
| Cannabinoid receptor 2 | |||
| Name: | Cannabinoid receptor 2 | ||
| Synonyms: | CANNABINOID CB2 | CB-2 | CB2 | CB2A | CB2B | CNR2 | CNR2_HUMAN | CX5 | Cannabinoid CB2 receptor | Cannabinoid receptor 2 (CB2) | Cannabinoid receptor 2 (CB2R) | hCB2 | ||
| Type: | G Protein-Coupled Receptor (GPCR) | ||
| Mol. Mass.: | 39690.94 | ||
| Organism: | Homo sapiens (Human) | ||
| Description: | P34972 | ||
| Residue: | 360 | ||
| Sequence: |
| ||
| BDBM50495627 | |||
| n/a | |||
| Name | BDBM50495627 | ||
| Synonyms: | CHEMBL3114173 | ||
| Type | Small organic molecule | ||
| Emp. Form. | C20H24N2O2 | ||
| Mol. Mass. | 324.4168 | ||
| SMILES | CC1CCC(CC1)NC(=O)c1cccn(Cc2ccccc2)c1=O |(3.98,-37.64,;5.52,-37.64,;6.29,-38.97,;7.83,-38.97,;8.6,-37.64,;7.83,-36.31,;6.29,-36.31,;10.15,-37.64,;10.91,-36.31,;10.15,-34.97,;12.46,-36.31,;13.23,-34.97,;14.77,-34.97,;15.54,-36.31,;14.77,-37.64,;15.54,-38.97,;17.09,-38.97,;17.86,-37.64,;19.4,-37.64,;20.17,-38.97,;19.4,-40.31,;17.86,-40.31,;13.23,-37.64,;12.46,-38.97,)| | ||
| Structure | 
| ||