| Reaction Details |
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 | Report a problem with these data |
| Target | D-alanyl-D-alanine carboxypeptidase DacA |
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| Ligand | BDBM50370584 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1289588 (CHEMBL3117907) |
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| KON | 620 M-1s-1 |
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| Citation |  Dave, K; Palzkill, T; Pratt, RF Neutral ?-Lactams Inactivate High Molecular Mass Penicillin-Binding Proteins of Class B1, Including PBP2a of MRSA. ACS Med Chem Lett5:154-7 (2014) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| D-alanyl-D-alanine carboxypeptidase DacA |
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| Name: | D-alanyl-D-alanine carboxypeptidase DacA |
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| Synonyms: | 3.4.16.4 | CPase | D-alanyl-D-alanine carboxypeptidase DacA | DACA_BACSU | DD-carboxypeptidase | DD-peptidase | PBP-5 | Penicillin-binding protein 5 | dacA |
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| Type: | PROTEIN |
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| Mol. Mass.: | 48633.42 |
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| Organism: | Bacillus subtilis (strain 168) |
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| Description: | ChEMBL_108029 |
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| Residue: | 443 |
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| Sequence: | MNIKKCKQLLMSLVVLTLAVTCLAPMSKAKAASDPIDINASAAIMIEASSGKILYSKNAD
KRLPIASMTKMMTEYLLLEAIDQGKVKWDQTYTPDDYVYEISQDNSLSNVPLRKDGKYTV
KELYQATAIYSANAAAIAIAEIVAGSETKFVEKMNAKAKELGLTDYKFVNATGLENKDLH
GHQPEGTSVNEESEVSAKDMAVLADHLITDYPEILETSSIAKTKFREGTDDEMDMPNWNF
MLKGLVSEYKKATVDGLKTGSTDSAGSCFTGTAERNGMRVITVVLNAKGNLHTGRFDETK
KMFDYAFDNFSMKEIYAEGDQVKGHKTISVDKGKEKEVGIVTNKAFSLPVKNGEEKNYKA
KVTLNKDNLTAPVKKGTKVGKLTAEYTGDEKDYGFLNSDLAGVDLVTKENVEKANWFVLT
MRSIGGFFAGIWGSIVDTVTGWF
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| BDBM50370584 |
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| n/a |
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| Name | BDBM50370584 |
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| Synonyms: | Beepen-VK | Betapen-VK | PENICILLIN V | Penapar-VK | Penicillin Phenoxymethyl |
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| Type | Small organic molecule |
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| Emp. Form. | C16H18N2O5S |
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| Mol. Mass. | 350.39 |
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| SMILES | CC1(C)S[C@@H]2[C@H](NC(=O)COc3ccccc3)C(=O)N2[C@H]1C(O)=O |r| |
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| Structure | 
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