| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Penicillin-binding protein 3 |
|---|
| Ligand | BDBM50370584 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_1289590 (CHEMBL3117909) |
|---|
| KON | 28 M-1s-1 |
|---|
| Citation |  Dave, K; Palzkill, T; Pratt, RF Neutral ?-Lactams Inactivate High Molecular Mass Penicillin-Binding Proteins of Class B1, Including PBP2a of MRSA. ACS Med Chem Lett5:154-7 (2014) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Penicillin-binding protein 3 |
|---|
| Name: | Penicillin-binding protein 3 |
|---|
| Synonyms: | PBP 3 | PBPC_BACSU | PSPB20 | Penicillin-binding protein 3 | Penicillin-binding protein C | pbpC | ycsM | yzsA | yzsA |
|---|
| Type: | PROTEIN |
|---|
| Mol. Mass.: | 74405.44 |
|---|
| Organism: | Bacillus subtilis (strain 168) |
|---|
| Description: | ChEMBL_108031 |
|---|
| Residue: | 668 |
|---|
| Sequence: | MLKKCILLVFLCVGLIGLIGCSKTDSPEDRMEAFVKQWNDQQFDDMYQSLTKDVKKEISK
KDFVNRYKAIYEQAGVKNLKVTAGEVDKDDQDNKTMKHIPYKVSMNTNAGKVSFKNTAVL
KLEKTDDEESWNIDWDPSFIFKQLADDKTVQIMSIEPKRGQIYDKNGKGLAVNTDVPEIG
IVPGELGDKKEKVIKELAKKLDLTEDDIKKKLDQGWVKDDSFVPLKKVKPDQEKLVSEAT
SLQGVTRTNVSSRYYPYGEKTAHLTGYVRAITAEELKKKKEGTYSDTSNIGIAGLENVYE
DKLRGTTGWKIYVPQTGEVIAEKKAKDGEDLHLTIDIKTQMKLYDELKDDSGAAVALQPK
TGETLALVSAPSYDPNGFIFGWSDKEWKKLNKDKNNPFSAKFNKTYAPGSTIKPIAAAIG
IKNGTLKADEKKTIKGKEWQKDSSWGGYSVTRVSERLQQVDLENALITSDNIYFAQNALD
MGADTFTKGLKTFGFSEDVPYEFPIQKSSIANDKLDSDILLADTGYGQGQMQMSPLHLAT
AYTPFVDNGDLVKPTLIKKDSQTADVWHKQVVTKEGAADITKGLKGVVEDERGSAYQPVV
KGITVAGKTGTAELKTSKDDKDGTENGWFVGYDYENKDLLVAMMIQNVQDRGGSHYVVEK
AKKQFQSN
|
|
|
|---|
| BDBM50370584 |
|---|
| n/a |
|---|
| Name | BDBM50370584 |
|---|
| Synonyms: | Beepen-VK | Betapen-VK | PENICILLIN V | Penapar-VK | Penicillin Phenoxymethyl |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C16H18N2O5S |
|---|
| Mol. Mass. | 350.39 |
|---|
| SMILES | CC1(C)S[C@@H]2[C@H](NC(=O)COc3ccccc3)C(=O)N2[C@H]1C(O)=O |r| |
|---|
| Structure | 
|
|---|
Search and Browse
