| Reaction Details |
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 | Report a problem with these data |
| Target | Thromboxane A2 receptor |
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| Ligand | BDBM50003776 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_209590 (CHEMBL814725) |
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| IC50 | 6±n/a nM |
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| Citation |  Soyka, R; Heckel, A; Nickl, J; Eisert, W; Müller, TH; Weisenberger, H 6,6-Disubstituted Hex-5-enoic acid derivatives as combined thromboxane A2 receptor antagonists and synthetase inhibitors. J Med Chem37:26-39 (1994) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| Thromboxane A2 receptor |
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| Name: | Thromboxane A2 receptor |
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| Synonyms: | Prostanoid TP receptor | TA2R_HUMAN | TBXA2R | TXA2-R | Thromboxane | Thromboxane A2 receptor | Thromboxane Beta |
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| Type: | Enyzme |
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| Mol. Mass.: | 37445.28 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P21731 |
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| Residue: | 343 |
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| Sequence: | MWPNGSSLGPCFRPTNITLEERRLIASPWFAASFCVVGLASNLLALSVLAGARQGGSHTR
SSFLTFLCGLVLTDFLGLLVTGTIVVSQHAALFEWHAVDPGCRLCRFMGVVMIFFGLSPL
LLGAAMASERYLGITRPFSRPAVASQRRAWATVGLVWAAALALGLLPLLGVGRYTVQYPG
SWCFLTLGAESGDVAFGLLFSMLGGLSVGLSFLLNTVSVATLCHVYHGQEAAQQRPRDSE
VEMMAQLLGIMVVASVCWLPLLVFIAQTVLRNPPAMSPAGQLSRTTEKELLIYLRVATWN
QILDPWVYILFRRAVLRRLQPRLSTRPRSLSLQPQLTQRSGLQ
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| BDBM50003776 |
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| n/a |
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| Name | BDBM50003776 |
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| Synonyms: | 8-(4-Chloro-benzenesulfonylamino)-4-(3-pyridin-3-yl-propyl)-octanoic acid | CGS-22652 | CHEMBL65414 |
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| Type | Small organic molecule |
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| Emp. Form. | C22H29ClN2O4S |
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| Mol. Mass. | 452.995 |
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| SMILES | OC(=O)CCC(CCCCNS(=O)(=O)c1ccc(Cl)cc1)CCCc1cccnc1 |
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| Structure | 
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