| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Protein Tat |
|---|
| Ligand | BDBM50045401 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEBML_209908 |
|---|
| IC50 | 8400±n/a nM |
|---|
| Citation |  Michne, WF; Schroeder, JD; Bailey, TR; Young, DC; Hughes, JV; Dutko, FJ Keto/enol epoxy steroids: a new structural class of HIV-1 Tat inhibitors. J Med Chem36:2701-2 (1993) [PubMed] |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Protein Tat |
|---|
| Name: | Protein Tat |
|---|
| Synonyms: | Human immunodeficiency virus type 1 Tat protein | Protein Tat | TAT_HV112 | Transactivating regulatory protein | tat |
|---|
| Type: | PROTEIN |
|---|
| Mol. Mass.: | 9771.75 |
|---|
| Organism: | Human immunodeficiency virus type 1 (isolate PCV12 group M subtype B)(HIV-1) |
|---|
| Description: | ChEMBL_199318 |
|---|
| Residue: | 86 |
|---|
| Sequence: | MEPVDPRLEPWKHPGSQPKTACTNCYCKKCCFHCQVCFITKALGISYGRKKRRQRRRAPQ
GSQTHQVSLSKQPTSQSRGDPTGPKE
|
|
|
|---|
| BDBM50045401 |
|---|
| n/a |
|---|
| Name | BDBM50045401 |
|---|
| Synonyms: | 17-Hydroxy-2-methanesulfonyl-10,13-dimethyl-tetradecahydro-20-oxa-cyclopropa[4,5]cyclopenta[a]phenanthren-3-one | CHEMBL3137862 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C20H30O5S |
|---|
| Mol. Mass. | 382.514 |
|---|
| SMILES | [H][C@@]12CC[C@H](O)[C@@]1(C)CC[C@@]1([H])[C@@]2([H])CC[C@]23OC2C(=O)C(C[C@]13C)S(C)(=O)=O |
|---|
| Structure | 
|
|---|
Search and Browse
