| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Beta-galactosidase |
|---|
| Ligand | BDBM50261442 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_1438445 (CHEMBL3384257) |
|---|
| IC50 | 22±n/a nM |
|---|
| Citation |  Fan, QH; Claunch, KA; Striegler, S Structure-activity relationship of highly potent galactonoamidine inhibitors toward ?-galactosidase (Aspergillus oryzae). J Med Chem57:8999-9009 (2014) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Beta-galactosidase |
|---|
| Name: | Beta-galactosidase |
|---|
| Synonyms: | 3.2.1.23 | Beta-galactosidase |
|---|
| Type: | PROTEIN |
|---|
| Mol. Mass.: | 100763.98 |
|---|
| Organism: | Aspergillus oryzae |
|---|
| Description: | ChEMBL_109122 |
|---|
| Residue: | 909 |
|---|
| Sequence: | MASLMKVYKLWVDIIAQNPANRHELTSQQRHVFSAEDPEKPLQDIVTWDEYSILVRGERI
LFFSGEFHPFRLPSPGLWLDVFQKIRALGYSGVSFYLMWGLLEGEPGHVRTEGVFALDGF
FNAASQAGIYLLARPGPYINAEVSGGGFPSWVQRIEGSVRTTDPTFLNATKNYISTIGEI
ISKVQITNGGPVILFQLENEYSICEGAPSHEELNFCLEKDYMAAIEQQFRDAEIVVPFVN
NDAVALGDWAPGTGQGAIDIYGFDNYPFGWGNGYASPENWTQITDPLTQYNFSQHQSMSP
GTPFSIIEFQGGAPDPWGGTGADVCAEMVSNIFARVFYKINYDFRITIFNLYMMLGGTNW
GNLGYSSGYTSYDVGAAIIEDRQITREKYSEIKLEAQFLQVSPAYITSKPHSPCSGCYTN
ASALMTTRLQGESTNFYIIRHSNYIVTQSTSYEWRANTSQGSITVPQPGGSSTLHGRDSK
FHVTDCDLGGINLIYPTAETFTWRRHGSKSVLVLYGGEDEIHEFAVDSNLGNATTIEGSN
VRLGKRGATFVVQWDHLDVYLLWRNEAYQYWVMDLPAPEPLDLHASPSRTNSSVIVKAGY
LLRNASISENTLHLTGDVNATSTVELISAPPGCCSDVLYDGNRLQNISNTNGRVSGVVPY
IDPKLAIPEMESLEWRYLDSLPEGEEKSLYLSTQGGYAYGHSVWLDSTYLGSWQGNPAIQ
NYNQTLQFPQSLQGDEHYVLTILIDNLGLDLNFELNTNTMKSPRGLLDYDLSGHNSWKIT
GNLGGEQYREHSRGPLNKGSTFVERQGYHLSGALNSTKAEWQTRTPQEGLSAAGVGLFAT
TFSLDYPQGYDIPTSVYVTIPTTHQSIVNNTGPQTEYPIPEGILNHHGGNHLAHHLLGSG
RKWGKAGRD
|
|
|
|---|
| BDBM50261442 |
|---|
| n/a |
|---|
| Name | BDBM50261442 |
|---|
| Synonyms: | CHEMBL3359682 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C14H26N2O4 |
|---|
| Mol. Mass. | 286.3672 |
|---|
| SMILES | OC[C@H]1N\C(=N/CC2CCCCCC2)[C@H](O)[C@@H](O)[C@H]1O |r| |
|---|
| Structure | 
|
|---|
Search and Browse
