| Reaction Details |
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 | Report a problem with these data |
| Target | G protein-coupled receptor |
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| Ligand | BDBM78940 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1456669 (CHEMBL3370504) |
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| EC50 | 330±n/a nM |
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| Citation |  Tschammer, N Allosteric modulation of the G protein-coupled US28 receptor of human cytomegalovirus: are the small-weight inverse agonist of US28 'camouflaged' agonists? Bioorg Med Chem Lett24:3744-7 (2014) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| G protein-coupled receptor |
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| Name: | G protein-coupled receptor |
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| Synonyms: | G protein-coupled receptor | US28 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 40950.37 |
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| Organism: | Human cytomegalovirus |
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| Description: | ChEMBL_109734 |
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| Residue: | 354 |
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| Sequence: | MTPTTTTAELTTEFDYDEDAAPCVLTDVLNQSKPVTLFLYGVVFLFGSIGNFLVIFTITW
RRRIQCSGDVYFINLAAADLLFVCTLPLWMQYLLDHNSLASVPCTLLTACFYVAMFASLC
FITEIALDRYYAIVYMRYRPVKQACLFSIFWWIFAVIIAIPHFMVVTKKNNQCMTDYDYL
EVSYPIILNVELMLGAFVIPLSVISYCYYRISRIVAVSQSRHKGRIVRVLIAVVLVFIIF
WLPYHLTLFVDTLKLLKWISSSCEFEKSLKRALILTESLAFCHCCLNPLLYVFVGTKFRQ
ELHCLLAEFRQRLFSRDVSWYHSMSFSRRSSPSRRETSSDTLSDEACRVSQIIP
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| BDBM78940 |
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| n/a |
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| Name | BDBM78940 |
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| Synonyms: | METHIOTHEPIN | MLS000859918 | Methiothepin mesylate salt | SMR000326779 | cid_3039995 | mesylic acid;1-methyl-4-[3-(methylthio)-5,6-dihydrobenzo[b][1]benzothiepin-5-yl]piperazine | methanesulfonic acid;1-methyl-4-(3-methylsulfanyl-5,6-dihydrobenzo[b][1]benzothiepin-5-yl)piperazine | methanesulfonic acid;1-methyl-4-[3-(methylthio)-5,6-dihydrobenzo[b][1]benzothiepin-5-yl]piperazine |
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| Type | Small organic molecule |
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| Emp. Form. | C20H24N2S2 |
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| Mol. Mass. | 356.548 |
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| SMILES | CSc1ccc2Sc3ccccc3CC(N3CCN(C)CC3)c2c1 |
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| Structure | 
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