| Reaction Details |
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 | Report a problem with these data |
| Target | G-protein coupled receptor homolog US28 |
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| Ligand | BDBM50497863 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1455744 (CHEMBL3366772) |
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| EC50 | 1500±n/a nM |
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| Citation |  Tschammer, N Allosteric modulation of the G protein-coupled US28 receptor of human cytomegalovirus: are the small-weight inverse agonist of US28 'camouflaged' agonists? Bioorg Med Chem Lett24:3744-7 (2014) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| G-protein coupled receptor homolog US28 |
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| Name: | G-protein coupled receptor homolog US28 |
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| Synonyms: | Human herpesvirus 5 chemokine receptor | US28 | US28_HCMVA |
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| Type: | PROTEIN |
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| Mol. Mass.: | 41070.46 |
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| Organism: | Human cytomegalovirus (strain AD169) (HHV-5) (Human herpesvirus 5) |
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| Description: | ChEMBL_322135 |
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| Residue: | 354 |
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| Sequence: | MTPTTTTAELTTEFDYDEDATPCVFTDVLNQSKPVTLFLYGVVFLFGSIGNFLVIFTITW
RRRIQCSGDVYFINLAAADLLFVCTLPLWMQYLLDHNSLASVPCTLLTACFYVAMFASLC
FITEIALDRYYAIVYMRYRPVKQACLFSIFWWIFAVIIAIPHFMVVTKKDNQCMTDYDYL
EVSYPIILNVELMLGAFVIPLSVISYCYYRISRIVAVSQSRHKGRIVRVLIAVVLVFIIF
WLPYHLTLFVDTLKLLKWISSSCEFERSLKRALILTESLAFCHCCLNPLLYVFVGTKFRQ
ELHCLLAEFRQRLFSRDVSWYHSMSFSRRSSPSRRETSSDTLSDEVCRVSQIIP
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| BDBM50497863 |
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| n/a |
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| Name | BDBM50497863 |
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| Synonyms: | CHEMBL1824269 |
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| Type | Small organic molecule |
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| Emp. Form. | C25H41N3O2 |
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| Mol. Mass. | 415.6119 |
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| SMILES | CCCCCCCCCC(=O)N(CCN(C)C)CC1(C)Cc2ccccc2C(=O)N1 |
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| Structure | 
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