| Reaction Details |
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 | Report a problem with these data |
| Target | Aromatic-L-amino-acid decarboxylase |
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| Ligand | BDBM50046351 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_36194 (CHEMBL649363) |
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| Ki | 24300±n/a nM |
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| Citation |  Zembower, DE; Gilbert, JA; Ames, MM Enantiospecific syntheses of alpha-(fluoromethyl)tryptophan analogues: interactions with tryptophan hydroxylase and aromatic L-amino acid decarboxylase. J Med Chem36:305-13 (1993) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| Aromatic-L-amino-acid decarboxylase |
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| Name: | Aromatic-L-amino-acid decarboxylase |
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| Synonyms: | DDC_MOUSE | DOPA decarboxylase | Ddc |
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| Type: | PROTEIN |
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| Mol. Mass.: | 53874.00 |
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| Organism: | Mus musculus |
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| Description: | ChEMBL_1333664 |
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| Residue: | 480 |
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| Sequence: | MDSREFRRRGKEMVDYIADYLDGIEGRPVYPDVEPGYLRPLIPATAPQEPETYEDIIKDI
EKIIMPGVTHWHSPYFFAYFPTASSYPAMLADMLCGAIGCIGFSWAASPACTELETVMMD
WLGKMLELPEAFLAGRAGEGGGVIQGSASEATLVALLAARTKVIRQLQAASPEFTQAAIM
EKLVAYTSDQAHSSVERAGLIGGIKLKAVPSDGNFSMRASALREALERDKAAGLIPFFVV
ATLGTTSCCSFDNLLEVGPICNQEGVWLHIDAAYAGSAFICPEFRYLLNGVEFADSFNFN
PHKWLLVNFDCSAMWVKRRTDLTGAFNMDPVYLKHSHQDSGFITDYRHWQIPLGRRFRSL
KMWFVFRMYGVKGLQAYIRKHVELSHEFESLVRQDPRFEICTEVILGLVCFRLKGSNELN
ETLLQRINSAKKIHLVPCRLRDKFVLRFAVCARTVESAHVQLAWEHISDLASSVLRAEKE
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| BDBM50046351 |
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| n/a |
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| Name | BDBM50046351 |
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| Synonyms: | 2-Amino-2-fluoromethyl-3-(5-hydroxy-1H-indol-3-yl)-propionic acid | CHEMBL108478 |
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| Type | Small organic molecule |
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| Emp. Form. | C12H13FN2O3 |
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| Mol. Mass. | 252.2416 |
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| SMILES | N[C@@](CF)(Cc1c[nH]c2ccc(O)cc12)C(O)=O |
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| Structure | 
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