| Reaction Details |
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 | Report a problem with these data |
| Target | Thromboxane A2 receptor |
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| Ligand | BDBM50008779 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_207650 (CHEMBL811632) |
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| Ki | 15.3±n/a nM |
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| Citation |  Nicolaï, E; Goyard, J; Benchetrit, T; Teulon, JM; Caussade, F; Virone, A; Delchambre, C; Cloarec, A Synthesis and structure-activity relationships of novel benzimidazole and imidazo[4,5-b]pyridine acid derivatives as thromboxane A2 receptor antagonists. J Med Chem36:1175-87 (1993) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| Thromboxane A2 receptor |
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| Name: | Thromboxane A2 receptor |
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| Synonyms: | Prostanoid TP receptor | TA2R_HUMAN | TBXA2R | TXA2-R | Thromboxane | Thromboxane A2 receptor | Thromboxane Beta |
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| Type: | Enyzme |
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| Mol. Mass.: | 37445.28 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P21731 |
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| Residue: | 343 |
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| Sequence: | MWPNGSSLGPCFRPTNITLEERRLIASPWFAASFCVVGLASNLLALSVLAGARQGGSHTR
SSFLTFLCGLVLTDFLGLLVTGTIVVSQHAALFEWHAVDPGCRLCRFMGVVMIFFGLSPL
LLGAAMASERYLGITRPFSRPAVASQRRAWATVGLVWAAALALGLLPLLGVGRYTVQYPG
SWCFLTLGAESGDVAFGLLFSMLGGLSVGLSFLLNTVSVATLCHVYHGQEAAQQRPRDSE
VEMMAQLLGIMVVASVCWLPLLVFIAQTVLRNPPAMSPAGQLSRTTEKELLIYLRVATWN
QILDPWVYILFRRAVLRRLQPRLSTRPRSLSLQPQLTQRSGLQ
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| BDBM50008779 |
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| n/a |
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| Name | BDBM50008779 |
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| Synonyms: | (+) [9-(4-Chloro-benzyl)-6-fluoro-2,3,4,9-tetrahydro-1H-carbazol-1-yl]-acetic acid | (-) [9-(4-Chloro-benzyl)-6-fluoro-2,3,4,9-tetrahydro-1H-carbazol-1-yl]-acetic acid | CHEMBL280107 | [9-(4-Chloro-benzyl)-6-fluoro-2,3,4,9-tetrahydro-1H-carbazol-1-yl]-acetic acid |
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| Type | Small organic molecule |
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| Emp. Form. | C21H19ClFNO2 |
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| Mol. Mass. | 371.832 |
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| SMILES | OC(=O)CC1CCCc2c1n(Cc1ccc(Cl)cc1)c1ccc(F)cc21 |
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| Structure | 
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