| Reaction Details |
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 | Report a problem with these data |
| Target | Thromboxane A2 receptor |
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| Ligand | BDBM50047301 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEBML_212937 |
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| Kd | 16±n/a nM |
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| Citation |  Misra, RN; Brown, BR; Sher, PM; Patel, MM; Hall, SE; Han, WC; Barrish, JC; Kocy, O; Harris, DN; Goldenberg, HJ Interphenylene 7-oxabicyclo[2.2.1]heptane oxazoles. Highly potent, selective, and long-acting thromboxane A2 receptor antagonists. J Med Chem36:1401-17 (1993) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| Thromboxane A2 receptor |
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| Name: | Thromboxane A2 receptor |
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| Synonyms: | Prostanoid TP receptor | TA2R_HUMAN | TBXA2R | TXA2-R | Thromboxane | Thromboxane A2 receptor | Thromboxane Beta |
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| Type: | Enyzme |
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| Mol. Mass.: | 37445.28 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P21731 |
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| Residue: | 343 |
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| Sequence: | MWPNGSSLGPCFRPTNITLEERRLIASPWFAASFCVVGLASNLLALSVLAGARQGGSHTR
SSFLTFLCGLVLTDFLGLLVTGTIVVSQHAALFEWHAVDPGCRLCRFMGVVMIFFGLSPL
LLGAAMASERYLGITRPFSRPAVASQRRAWATVGLVWAAALALGLLPLLGVGRYTVQYPG
SWCFLTLGAESGDVAFGLLFSMLGGLSVGLSFLLNTVSVATLCHVYHGQEAAQQRPRDSE
VEMMAQLLGIMVVASVCWLPLLVFIAQTVLRNPPAMSPAGQLSRTTEKELLIYLRVATWN
QILDPWVYILFRRAVLRRLQPRLSTRPRSLSLQPQLTQRSGLQ
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| BDBM50047301 |
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| n/a |
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| Name | BDBM50047301 |
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| Synonyms: | CHEMBL280786 | [3-(2-{3-[4-(4-Cyclohexyl-butylcarbamoyl)-oxazol-2-yl]-7-oxa-bicyclo[2.2.1]hept-2-yl}-ethyl)-phenyl]-acetic acid |
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| Type | Small organic molecule |
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| Emp. Form. | C30H40N2O5 |
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| Mol. Mass. | 508.649 |
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| SMILES | OC(=O)Cc1cccc(CCC2C3CCC(O3)C2c2nc(co2)C(=O)NCCCCC2CCCCC2)c1 |TLB:10:11:16:14.13,THB:18:17:16:14.13| |
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| Structure | 
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