| Reaction Details |
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 | Report a problem with these data |
| Target | Alpha-2C adrenergic receptor |
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| Ligand | BDBM344422 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1539122 (CHEMBL3738630) |
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| Ki | <100±n/a nM |
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| Citation |  Cinelli, MA; Li, H; Pensa, AV; Kang, S; Roman, LJ; Martásek, P; Poulos, TL; Silverman, RB Phenyl Ether- and Aniline-Containing 2-Aminoquinolines as Potent and Selective Inhibitors of Neuronal Nitric Oxide Synthase. J Med Chem58:8694-712 (2015) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Alpha-2C adrenergic receptor |
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| Name: | Alpha-2C adrenergic receptor |
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| Synonyms: | ADA2C_HUMAN | ADRA2C | ADRA2L2 | ADRA2RL2 | Adrenergic alpha2C | Adrenergic receptor | Adrenergic receptor alpha | Adrenergic, alpha-2C-, receptor | Alpha-2 adrenergic receptor subtype C4 | Alpha-2C adrenoceptor | Alpha-2C adrenoreceptor | adrenergic, alpha-2C-, receptor [Homo sapiens] |
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| Type: | Enzyme |
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| Mol. Mass.: | 49552.32 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P18825 |
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| Residue: | 462 |
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| Sequence: | MASPALAAALAVAAAAGPNASGAGERGSGGVANASGASWGPPRGQYSAGAVAGLAAVVGF
LIVFTVVGNVLVVIAVLTSRALRAPQNLFLVSLASADILVATLVMPFSLANELMAYWYFG
QVWCGVYLALDVLFCTSSIVHLCAISLDRYWSVTQAVEYNLKRTPRRVKATIVAVWLISA
VISFPPLVSLYRQPDGAAYPQCGLNDETWYILSSCIGSFFAPCLIMGLVYARIYRVAKLR
TRTLSEKRAPVGPDGASPTTENGLGAAAGAGENGHCAPPPADVEPDESSAAAERRRRRGA
LRRGGRRRAGAEGGAGGADGQGAGPGAAESGALTASRSPGPGGRLSRASSRSVEFFLSRR
RRARSSVCRRKVAQAREKRFTFVLAVVMGVFVLCWFPFFFSYSLYGICREACQVPGPLFK
FFFWIGYCNSSLNPVIYTVFNQDFRRSFKHILFRRRRRGFRQ
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| BDBM344422 |
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| n/a |
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| Name | BDBM344422 |
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| Synonyms: | US9783500, Compound 17 |
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| Type | Small organic molecule |
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| Emp. Form. | C18H18ClN3O |
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| Mol. Mass. | 327.808 |
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| SMILES | CNCc1cc(OCc2ccc3ccc(N)nc3c2)ccc1Cl |
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| Structure | 
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