| Reaction Details |
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 | Report a problem with these data |
| Target | Retinoic acid receptor beta |
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| Ligand | BDBM50048291 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_195496 (CHEMBL798917) |
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| Ki | 2480±n/a nM |
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| Citation |  Charpentier, B; Bernardon, JM; Eustache, J; Millois, C; Martin, B; Michel, S; Shroot, B Synthesis, structure-affinity relationships, and biological activities of ligands binding to retinoic acid receptor subtypes. J Med Chem38:4993-5006 (1996) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| Retinoic acid receptor beta |
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| Name: | Retinoic acid receptor beta |
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| Synonyms: | HAP | HBV-activated protein | NR1B2 | Nuclear receptor subfamily 1 group B member 2 | RAR-beta | RAR-epsilon | RARB | RARB_HUMAN | Retinoic acid receptor RXR-alpha/Retinoic acid receptor beta | Retinoic acid receptor beta | Retinoid receptor |
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| Type: | PROTEIN |
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| Mol. Mass.: | 50498.70 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_1458015 |
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| Residue: | 455 |
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| Sequence: | MTTSGHACPVPAVNGHMTHYPATPYPLLFPPVIGGLSLPPLHGLHGHPPPSGCSTPSPAT
IETQSTSSEELVPSPPSPLPPPRVYKPCFVCQDKSSGYHYGVSACEGCKGFFRRSIQKNM
IYTCHRDKNCVINKVTRNRCQYCRLQKCFEVGMSKESVRNDRNKKKKETSKQECTESYEM
TAELDDLTEKIRKAHQETFPSLCQLGKYTTNSSADHRVRLDLGLWDKFSELATKCIIKIV
EFAKRLPGFTGLTIADQITLLKAACLDILILRICTRYTPEQDTMTFSDGLTLNRTQMHNA
GFGPLTDLVFTFANQLLPLEMDDTETGLLSAICLICGDRQDLEEPTKVDKLQEPLLEALK
IYIRKRRPSKPHMFPKILMKITDLRSISAKGAERVITLKMEIPGSMPPLIQEMLENSEGH
EPLTPSSSGNTAEHSPSISPSSVENSGVSQSPLVQ
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| BDBM50048291 |
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| n/a |
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| Name | BDBM50048291 |
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| Synonyms: | 6-(3-Adamantan-1-yl-4-hydroxy-phenyl)-naphthalene-2-carboxylic acid | 6-[3'-(1-adamantyl)-4'-hydroxyphenyl]-2-naphthalenecarboxylic acid | 6-[3'-(1-adamantyl)-4'-hydroxyphenyl]-2-naphthoic acid | CHEMBL1180 | O-Demethylated Adapalene |
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| Type | Small organic molecule |
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| Emp. Form. | C27H26O3 |
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| Mol. Mass. | 398.4935 |
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| SMILES | OC(=O)c1ccc2cc(ccc2c1)-c1ccc(O)c(c1)C12CC3CC(CC(C3)C1)C2 |TLB:18:20:23:27.26.25,THB:21:22:25:29.20.28,21:20:23.22.27:25,28:20:23:27.26.25,28:26:23:29.21.20| |
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| Structure | 
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