| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Adenosine receptor A2a |
|---|
| Ligand | BDBM50048451 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_31060 (CHEMBL641344) |
|---|
| Ki | 6040±n/a nM |
|---|
| Citation |  van Rhee, AM; Siddiqi, SM; Melman, N; Shi, D; Padgett, WL; Daly, JW; Jacobson, KA Tetrahydrobenzothiophenone derivatives as a novel class of adenosine receptor antagonists. J Med Chem39:398-406 (1996) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Adenosine receptor A2a |
|---|
| Name: | Adenosine receptor A2a |
|---|
| Synonyms: | AA2AR_RAT | ADENOSINE A2a | Adenosine A2 receptor | Adenosine A2a receptor (A2a) | Adenosine Receptors A2a (A2a) | Adenosine receptor A2a and A3 | Adenosine receptors A2a | Adora2a | Rat striatal adenosine A2a receptor |
|---|
| Type: | G Protein-Coupled Receptor (GPCR) |
|---|
| Mol. Mass.: | 45015.65 |
|---|
| Organism: | Rattus norvegicus (rat) |
|---|
| Description: | Rat A2A receptors expressed in CHO cells. |
|---|
| Residue: | 410 |
|---|
| Sequence: | MGSSVYITVELAIAVLAILGNVLVCWAVWINSNLQNVTNFFVVSLAAADIAVGVLAIPFA
ITISTGFCAACHGCLFFACFVLVLTQSSIFSLLAIAIDRYIAIRIPLRYNGLVTGVRAKG
IIAICWVLSFAIGLTPMLGWNNCSQKDGNSTKTCGEGRVTCLFEDVVPMNYMVYYNFFAF
VLLPLLLMLAIYLRIFLAARRQLKQMESQPLPGERTRSTLQKEVHAAKSLAIIVGLFALC
WLPLHIINCFTFFCSTCRHAPPWLMYLAIILSHSNSVVNPFIYAYRIREFRQTFRKIIRT
HVLRRQEPFQAGGSSAWALAAHSTEGEQVSLRLNGHPLGVWANGSATHSGRRPNGYTLGL
GGGGSAQGSPRDVELPTQERQEGQEHPGLRGHLVQARVGASSWSSEFAPS
|
|
|
|---|
| BDBM50048451 |
|---|
| n/a |
|---|
| Name | BDBM50048451 |
|---|
| Synonyms: | 3-Allylsulfanyl-4-oxo-4,5,6,7-tetrahydro-benzo[c]thiophene-1-carboxylic acid ethyl ester | CHEMBL130787 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C14H16O3S2 |
|---|
| Mol. Mass. | 296.405 |
|---|
| SMILES | CCOC(=O)c1sc(SCC=C)c2c1CCCC2=O |
|---|
| Structure | 
|
|---|
Search and Browse
