| Reaction Details |
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 | Report a problem with these data |
| Target | Zinc metalloproteinase dpy-31 |
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| Ligand | BDBM50499819 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1541441 (CHEMBL3743609) |
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| IC50 | >500000±n/a nM |
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| Citation |  France, DJ; Stepek, G; Houston, DR; Williams, L; McCormack, G; Walkinshaw, MD; Page, AP Identification and activity of inhibitors of the essential nematode-specific metalloprotease DPY-31. Bioorg Med Chem Lett25:5752-5 (2015) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Zinc metalloproteinase dpy-31 |
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| Name: | Zinc metalloproteinase dpy-31 |
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| Synonyms: | 3.4.24.- | NAS35_TELCI | Nematode astacin 35 | Procollagen C-proteinase | Zinc metalloproteinase dpy-31 | dpy-31 | nas-35 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 69706.72 |
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| Organism: | Teladorsagia circumcincta |
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| Description: | ChEMBL_116693 |
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| Residue: | 614 |
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| Sequence: | MSLLRCTTLLLVVVAIALPPCILGYSLHDGSRLDDFLTESAADRRPRRPTTAAQRRLMGL
TEEQYKTVHFYLNKLKELGNQRHPEGYDKDTTKDEADKWRKRMRDDIEGELLNPEEYGRH
FEGDIILFPEQAKQIYENALKTGQRRVKRKFIGSDLRRWDPTRPIVYSFDGSHTSREQRI
IELALEHWHNITCLNFVRNDNANSGNRIVFTDVDGCASNVGRHPLGEEQLVSLAPECIRL
GVIAHEVAHALGFWHEQSRPDRDQFVNVRWENIDKDSKGQFLKEDPDDVDNAGVPYDYGS
IMHYRSKAFSRYDDLYTISTFVTDYQKTIGQRDQLSFNDIRLMNKIYCSNVCSRKLPCQR
GGYTDPRRCDRCRCPDGFTGQFCEQVMPGYGAVCGGRIQVNGGWTKFSSPGYPREFKEGQ
ECSWLLVAPHGQVVEMQFIGEFEMYCKVRHSLCMDYVEVRNSTDFANTGMRYCCYGTPST
SIRSATTDLVVLFRSFYRGGRGFEARARALPANGQWASWSPWTPCTASCGACGSRMRTRV
CSHGACAGEPVENQVCNTHPCNGLCAHKKTEDGECGGFLALLRGVRCKQERTVMEPCENA
CCPGFSVVGGRCVR
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| BDBM50499819 |
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| n/a |
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| Name | BDBM50499819 |
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| Synonyms: | CHEMBL3740244 |
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| Type | Small organic molecule |
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| Emp. Form. | C37H52N5O9P |
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| Mol. Mass. | 741.8106 |
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| SMILES | COC(=O)[C@@H]1CCCN1C(=O)[C@H](C)CP(O)(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CCCCN)NC(=O)[C@@H]1CCCN1C(=O)OCc1ccccc1 |r| |
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| Structure | 
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