| Reaction Details |
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 | Report a problem with these data |
| Target | Amine oxidase [flavin-containing] B |
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| Ligand | BDBM50049686 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_124230 (CHEMBL733984) |
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| IC50 | 60±n/a nM |
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| Citation |  Harfenist, M; Heuser, DJ; Joyner, CT; Batchelor, JF; White, HL Selective inhibitors of monoamine oxidase. 3. Structure-activity relationship of tricyclics bearing imidazoline, oxadiazole, or tetrazole groups. J Med Chem39:1857-63 (1996) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Amine oxidase [flavin-containing] B |
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| Name: | Amine oxidase [flavin-containing] B |
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| Synonyms: | AOFB_RAT | Amine oxidase (flavin-containing) B | Amine oxidase [flavin-containing] B | Maob | Monoamine Oxidase Type B (MAO-B) | Monoamine oxidase | Monoamine oxidase B (MAO-B) | Monoamine oxidase B (rMAO-B) | Monoamine oxidase type B (MAOB) | Monoamine oxidase-B (MAO-B) |
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| Type: | Enzyme |
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| Mol. Mass.: | 58469.65 |
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| Organism: | Rattus norvegicus (rat) |
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| Description: | P19643 |
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| Residue: | 520 |
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| Sequence: | MSNKCDVIVVGGGISGMAAAKLLHDCGLSVVVLEARDRVGGRTYTIRNKNVKYVDLGGSY
VGPTQNRILRLAKELGLETYKVNEVERLIHFVKGKSYAFRGPFPPVWNPITYLDYNNLWR
TMDEMGQEIPSDAPWKAPLAEEWDYMTMKELLDKICWTNSTKQIATLFVNLCVTAETHEV
SALWFLWYVKQCGGTTRIISTTNGGQERKFIGGSGQVSERIKDILGDRVKLERPVIHIDQ
TGENVVVKTLNHEIYEAKYVISAIPPVLGMKIHHSPPLPILRNQLITRVPLGSVIKCMVY
YKEPFWRKKDFCGTMVIEGEEAPIAYTLDDTKPDGSCAAIMGFILAHKARKLVRLTKEER
LRKLCELYAKVLNSQEALQPVHYEEKNWCEEQYSGGCYTAYFPPGILTQYGRVLRQPVGK
IFFAGTETASHWSGYMEGAVEAGERAAREILHAIGKIPEDEIWQPEPESVDVPARPITNT
FLERHLPSVPGLLKLLGLTTILSATALGFLAHKKGLFVRF
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| BDBM50049686 |
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| n/a |
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| Name | BDBM50049686 |
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| Synonyms: | 2-Methoxy-6-(2-methyl-2H-tetrazol-5-yl)-10,10-dioxo-10H-10lambda*6*-thioxanthen-9-one | CHEMBL52887 |
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| Type | Small organic molecule |
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| Emp. Form. | C16H12N4O4S |
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| Mol. Mass. | 356.356 |
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| SMILES | COc1ccc2c(c1)C(=O)c1ccc(cc1S2(=O)=O)-c1nnn(C)n1 |
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| Structure | 
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