| Reaction Details |
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 | Report a problem with these data |
| Target | D(2) dopamine receptor |
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| Ligand | BDBM50050462 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_60202 (CHEMBL672164) |
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| Ki | 71±n/a nM |
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| Citation |  Kulagowski, JJ; Broughton, HB; Curtis, NR; Mawer, IM; Ridgill, MP; Baker, R; Emms, F; Freedman, SB; Marwood, R; Patel, S; Patel, S; Ragan, CI; Leeson, PD 3-((4-(4-Chlorophenyl)piperazin-1-yl)-methyl)-1H-pyrrolo-2,3-b-pyridine: an antagonist with high affinity and selectivity for the human dopamine D4 receptor. J Med Chem39:1941-2 (1996) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| D(2) dopamine receptor |
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| Name: | D(2) dopamine receptor |
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| Synonyms: | D(2) dopamine receptor | DOPAMINE D2 | DOPAMINE D2 Long | DOPAMINE D2 Short | DRD2 | DRD2_HUMAN | Dopamine D2 receptor | Dopamine D2 receptor (D2) | Dopamine D2 receptor (D2R) | Dopamine D2A | Dopamine2-like | d2 |
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| Type: | Cell-surface receptors |
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| Mol. Mass.: | 50647.10 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P14416 |
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| Residue: | 443 |
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| Sequence: | MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVS
REKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTA
SILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQN
ECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPL
KGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPP
SHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSR
RKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSA
VNPIIYTTFNIEFRKAFLKILHC
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| BDBM50050462 |
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| n/a |
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| Name | BDBM50050462 |
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| Synonyms: | 3-[4-(4-Chloro-phenyl)-piperazin-1-ylmethyl]-1H-indole | CHEMBL268799 |
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| Type | Small organic molecule |
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| Emp. Form. | C19H20ClN3 |
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| Mol. Mass. | 325.835 |
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| SMILES | Clc1ccc(cc1)N1CCN(Cc2c[nH]c3ccccc23)CC1 |
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| Structure | 
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