| Reaction Details |
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 | Report a problem with these data |
| Target | Neuromedin-U receptor 1 |
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| Ligand | BDBM50500789 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1550246 (CHEMBL3760529) |
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| EC50 | 7943±n/a nM |
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| Citation |  Micewicz, ED; Bahattab, OS; Willars, GB; Waring, AJ; Navab, M; Whitelegge, JP; McBride, WH; Ruchala, P Small lipidated anti-obesity compounds derived from neuromedin U. Eur J Med Chem101:616-26 (2015) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Neuromedin-U receptor 1 |
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| Name: | Neuromedin-U receptor 1 |
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| Synonyms: | G-protein coupled receptor 66 | G-protein coupled receptor FM-3 | GPR66 | NMU-R1 | NMUR1 | NMUR1_HUMAN | Neuromedin-U receptor 1 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 47370.42 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_103121 |
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| Residue: | 426 |
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| Sequence: | MTPLCLNCSVLPGDLYPGGARNPMACNGSAARGHFDPEDLNLTDEALRLKYLGPQQTELF
MPICATYLLIFVVGAVGNGLTCLVILRHKAMRTPTNYYLFSLAVSDLLVLLVGLPLELYE
MWHNYPFLLGVGGCYFRTLLFEMVCLASVLNVTALSVERYVAVVHPLQARSMVTRAHVRR
VLGAVWGLAMLCSLPNTSLHGIRQLHVPCRGPVPDSAVCMLVRPRALYNMVVQTTALLFF
CLPMAIMSVLYLLIGLRLRRERLLLMQEAKGRGSAAARSRYTCRLQQHDRGRRQVTKMLF
VLVVVFGICWAPFHADRVMWSVVSQWTDGLHLAFQHVHVISGIFFYLGSAANPVLYSLMS
SRFRETFQEALCLGACCHRLRPRHSSHSLSRMTTGSTLCDVGSLGSWVHPLAGNDGPEAQ
QETDPS
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| BDBM50500789 |
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| n/a |
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| Name | BDBM50500789 |
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| Synonyms: | CHEMBL4299249 |
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| Type | Small organic molecule |
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| Emp. Form. | C93H143N19O12S3 |
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| Mol. Mass. | 1815.446 |
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| SMILES | [H][C@]12Cc3ccccc3CN1C(=O)[C@@H](CCCNC(N)=N)NC(=O)[C@@H](Cc1ccccc1)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](Cc1ccccc1)NC(=O)CCCCCNC(=O)[C@@H](N)CSCc1cc(CSCCCCCCCCCCCCCCCC)cc(CSC[C@H](NC(=O)CCCCCNC(=O)[C@@H](CC(N)=O)NC(=O)[C@@H](CCCNC(N)=N)NC2=O)C(N)=O)c1 |r| |
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| Structure | 
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