| Reaction Details |
|---|
 | Report a problem with these data |
| Target | D(3) dopamine receptor |
|---|
| Ligand | BDBM85067 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_62752 (CHEMBL674593) |
|---|
| Ki | 240±n/a nM |
|---|
| Citation |  TenBrink, RE; Bergh, CL; Duncan, JN; Harris, DW; Huff, RM; Lahti, RA; Lawson, CF; Lutzke, BS; Martin, IJ; Rees, SA; Schlachter, SK; Sih, JC; Smith, MW (S)-(-)-4-[4-[2-(isochroman-1-yl)ethyl]-piperazin-1-yl] benzenesulfonamide, a selective dopamine D4 antagonist. J Med Chem39:2435-7 (1996) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| D(3) dopamine receptor |
|---|
| Name: | D(3) dopamine receptor |
|---|
| Synonyms: | DOPAMINE D3 | DRD3_RAT | Dopamine D3 receptor | Drd3 |
|---|
| Type: | Protein |
|---|
| Mol. Mass.: | 49540.58 |
|---|
| Organism: | Rattus norvegicus (Rat) |
|---|
| Description: | P19020 |
|---|
| Residue: | 446 |
|---|
| Sequence: | MAPLSQISTHLNSTCGAENSTGVNRARPHAYYALSYCALILAIIFGNGLVCAAVLRERAL
QTTTNYLVVSLAVADLLVATLVMPWVVYLEVTGGVWNFSRICCDVFVTLDVMMCTASILN
LCAISIDRYTAVVMPVHYQHGTGQSSCRRVALMITAVWVLAFAVSCPLLFGFNTTGDPSI
CSISNPDFVIYSSVVSFYVPFGVTVLVYARIYIVLRQRQRKRILTRQNSQCISIRPGFPQ
QSSCLRLHPIRQFSIRARFLSDATGQMEHIEDKQYPQKCQDPLLSHLQPPSPGQTHGGLK
RYYSICQDTALRHPSLEGGAGMSPVERTRNSLSPTMAPKLSLEVRKLSNGRLSTSLRLGP
LQPRGVPLREKKATQMVVIVLGAFIVCWLPFFLTHVLNTHCQACHVSPELYRATTWLGYV
NSALNPVIYTTFNVEFRKAFLKILSC
|
|
|
|---|
| BDBM85067 |
|---|
| n/a |
|---|
| Name | BDBM85067 |
|---|
| Synonyms: | CAS_170856-41-4 | CHEMBL81330 | PNU 96415E | PNU-96415E |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C21H25FN2O |
|---|
| Mol. Mass. | 340.4344 |
|---|
| SMILES | Fc1ccc(cc1)N1CCN(CCC2OCCc3ccccc23)CC1 |
|---|
| Structure | 
|
|---|
Search and Browse
