Reaction Details |
| Report a problem with these data |
Target | Gag-Pol polyprotein [489-587] |
---|
Ligand | BDBM50053913 |
---|
Substrate/Competitor | n/a |
---|
Meas. Tech. | ChEMBL_157546 (CHEMBL764930) |
---|
Ki | 1500±n/a nM |
---|
Citation | Romines, KR; Morris, JK; Howe, WJ; Tomich, PK; Horng, MM; Chong, KT; Hinshaw, RR; Anderson, DJ; Strohbach, JW; Turner, SR; Mizsak, SA Cycloalkylpyranones and cycloalkyldihydropyrones as HIV protease inhibitors: exploring the impact of ring size on structure-activity relationships. J Med Chem39:4125-30 (1996) [PubMed] Article |
---|
More Info.: | Get all data from this article, Assay Method |
---|
|
Gag-Pol polyprotein [489-587] |
---|
Name: | Gag-Pol polyprotein [489-587] |
Synonyms: | Human immunodeficiency virus type 1 protease | POL_HV1H2 | Pol polyprotein | gag-pol |
Type: | Enzyme Subunit |
Mol. Mass.: | 10781.16 |
Organism: | Human immunodeficiency virus type 1 |
Description: | P04585[489-587] |
Residue: | 99 |
Sequence: | PQVTLWQRPLVTIKIGGQLKEALLDTGADDTVLEEMSLPGRWKPKMIGGIGGFIKVRQYD
QILIEICGHKAIGTVLVGPTPVNIIGRNLLTQIGCTLNF
|
|
|
BDBM50053913 |
---|
n/a |
---|
Name | BDBM50053913 |
Synonyms: | 3-(2,2-Dimethyl-1-phenyl-propyl)-4-hydroxy-4a,5,6,7,8,9,10,10a-octahydro-cycloocta[b]pyran-2-one | CHEMBL133951 |
Type | Small organic molecule |
Emp. Form. | C22H30O3 |
Mol. Mass. | 342.4718 |
SMILES | CC(C)(C)C(C1C(=O)OC2CCCCCCC2C1=O)c1ccccc1 |
Structure |
|