| Reaction Details |
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 | Report a problem with these data |
| Target | Gag-Pol polyprotein [489-587] |
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| Ligand | BDBM50053916 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_157546 (CHEMBL764930) |
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| Ki | 0.065±n/a nM |
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| Citation |  Romines, KR; Morris, JK; Howe, WJ; Tomich, PK; Horng, MM; Chong, KT; Hinshaw, RR; Anderson, DJ; Strohbach, JW; Turner, SR; Mizsak, SA Cycloalkylpyranones and cycloalkyldihydropyrones as HIV protease inhibitors: exploring the impact of ring size on structure-activity relationships. J Med Chem39:4125-30 (1996) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Gag-Pol polyprotein [489-587] |
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| Name: | Gag-Pol polyprotein [489-587] |
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| Synonyms: | Human immunodeficiency virus type 1 protease | POL_HV1H2 | Pol polyprotein | gag-pol |
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| Type: | Enzyme Subunit |
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| Mol. Mass.: | 10781.16 |
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| Organism: | Human immunodeficiency virus type 1 |
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| Description: | P04585[489-587] |
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| Residue: | 99 |
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| Sequence: | PQVTLWQRPLVTIKIGGQLKEALLDTGADDTVLEEMSLPGRWKPKMIGGIGGFIKVRQYD
QILIEICGHKAIGTVLVGPTPVNIIGRNLLTQIGCTLNF
|
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| BDBM50053916 |
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| n/a |
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| Name | BDBM50053916 |
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| Synonyms: | 4-Cyano-N-{3-[1-(4-hydroxy-2-oxo-5,6,7,8-tetrahydro-2H-chromen-3-yl)-propyl]-phenyl}-benzenesulfonamide | CHEMBL129900 |
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| Type | Small organic molecule |
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| Emp. Form. | C25H24N2O5S |
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| Mol. Mass. | 464.533 |
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| SMILES | CCC(c1cccc(NS(=O)(=O)c2ccc(cc2)C#N)c1)c1c(O)c2CCCCc2oc1=O |
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| Structure | 
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