| Reaction Details |
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 | Report a problem with these data |
| Target | D(2) dopamine receptor |
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| Ligand | BDBM50054342 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_60222 (CHEMBL672183) |
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| Ki | 4.94±n/a nM |
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| Citation |  Malmberg, A; Höök, BB; Johansson, AM; Hacksell, U Novel (R)-2-amino-5-fluorotetralins: dopaminergic antagonists and inverse agonists. J Med Chem39:4421-9 (1996) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| D(2) dopamine receptor |
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| Name: | D(2) dopamine receptor |
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| Synonyms: | D(2) dopamine receptor | DOPAMINE D2 | DOPAMINE D2 Long | DOPAMINE D2 Short | DRD2 | DRD2_HUMAN | Dopamine D2 receptor | Dopamine D2 receptor (D2) | Dopamine D2 receptor (D2R) | Dopamine D2A | Dopamine2-like | d2 |
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| Type: | Cell-surface receptors |
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| Mol. Mass.: | 50647.10 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P14416 |
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| Residue: | 443 |
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| Sequence: | MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVS
REKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTA
SILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQN
ECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPL
KGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPP
SHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSR
RKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSA
VNPIIYTTFNIEFRKAFLKILHC
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| BDBM50054342 |
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| n/a |
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| Name | BDBM50054342 |
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| Synonyms: | 8-{4-[((R)-5-Fluoro-1,2,3,4-tetrahydro-naphthalen-2-yl)-propyl-amino]-butyl}-8-aza-spiro[4.5]decane-7,9-dione | CHEMBL138998 |
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| Type | Small organic molecule |
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| Emp. Form. | C26H37FN2O2 |
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| Mol. Mass. | 428.5826 |
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| SMILES | CCCN(CCCCN1C(=O)CC2(CCCC2)CC1=O)[C@@H]1CCc2c(F)cccc2C1 |
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| Structure | 
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