| Reaction Details |
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 | Report a problem with these data |
| Target | Hexokinase-2 |
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| Ligand | BDBM49122 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1821937 (CHEMBL4321597) |
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| IC50 | 5520±n/a nM |
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| Citation |  Song, YJ; Zheng, HB; Peng, AH; Ma, JH; Lu, DD; Li, X; Zhang, HY; Xie, WD Strepantibins A-C: Hexokinase II Inhibitors from a Mud Dauber Wasp Associated Streptomyces sp. J Nat Prod82:1114-1119 (2019) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Hexokinase-2 |
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| Name: | Hexokinase-2 |
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| Synonyms: | HK II | HK2 | HXK2_HUMAN | Hexokinase type II | Hexokinase-2 | Muscle form hexokinase |
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| Type: | PROTEIN |
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| Mol. Mass.: | 102369.70 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_11422 |
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| Residue: | 917 |
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| Sequence: | MIASHLLAYFFTELNHDQVQKVDQYLYHMRLSDETLLEISKRFRKEMEKGLGATTHPTAA
VKMLPTFVRSTPDGTEHGEFLALDLGGTNFRVLWVKVTDNGLQKVEMENQIYAIPEDIMR
GSGTQLFDHIAECLANFMDKLQIKDKKLPLGFTFSFPCHQTKLDESFLVSWTKGFKSSGV
EGRDVVALIRKAIQRRGDFDIDIVAVVNDTVGTMMTCGYDDHNCEIGLIVGTGSNACYME
EMRHIDMVEGDEGRMCINMEWGAFGDDGSLNDIRTEFDQEIDMGSLNPGKQLFEKMISGM
YMGELVRLILVKMAKEELLFGGKLSPELLNTGRFETKDISDIEGEKDGIRKAREVLMRLG
LDPTQEDCVATHRICQIVSTRSASLCAATLAAVLQRIKENKGEERLRSTIGVDGSVYKKH
PHFAKRLHKTVRRLVPGCDVRFLRSEDGSGKGAAMVTAVAYRLADQHRARQKTLEHLQLS
HDQLLEVKRRMKVEMERGLSKETHASAPVKMLPTYVCATPDGTEKGDFLALDLGGTNFRV
LLVRVRNGKWGGVEMHNKIYAIPQEVMHGTGDELFDHIVQCIADFLEYMGMKGVSLPLGF
TFSFPCQQNSLDESILLKWTKGFKASGCEGEDVVTLLKEAIHRREEFDLDVVAVVNDTVG
TMMTCGFEDPHCEVGLIVGTGSNACYMEEMRNVELVEGEEGRMCVNMEWGAFGDNGCLDD
FRTEFDVAVDELSLNPGKQRFEKMISGMYLGEIVRNILIDFTKRGLLFRGRISERLKTRG
IFETKFLSQIESDCLALLQVRAILQHLGLESTCDDSIIVKEVCTVVARRAAQLCGAGMAA
VVDRIRENRGLDALKVTVGVDGTLYKLHPHFAKVMHETVKDLAPKCDVSFLQSEDGSGKG
AALITAVACRIREAGQR
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| BDBM49122 |
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| n/a |
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| Name | BDBM49122 |
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| Synonyms: | 2-amino-3-hydroxy-N'-(2,3,4-trihydroxybenzyl)propionohydrazide;hydrochloride | 2-amino-3-hydroxy-N'-[(2,3,4-trihydroxyphenyl)methyl]propanehydrazide;hydrochloride | 2-azanyl-3-oxidanyl-N'-[[2,3,4-tris(oxidanyl)phenyl]methyl]propanehydrazide;hydrochloride | BENSERAZIDE HYDROCHLORIDE | Benserazide | MLS000028424 | SMR000058421 | cid_26964 |
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| Type | Small organic molecule |
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| Emp. Form. | C10H15N3O5 |
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| Mol. Mass. | 257.2432 |
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| SMILES | NC(CO)C(=O)NNCc1ccc(O)c(O)c1O |
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| Structure | 
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