Reaction Details |
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Target | Mu-type opioid receptor |
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Ligand | BDBM50057389 |
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Substrate/Competitor | n/a |
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Meas. Tech. | ChEMBL_145162 (CHEMBL753422) |
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Ki | 1.5±n/a nM |
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Citation | Arttamangkul, S; Ishmael, JE; Murray, TF; Grandy, DK; DeLander, GE; Kieffer, BL; Aldrich, JV Synthesis and opioid activity of conformationally constrained dynorphin A analogues. 2. Conformational constraint in the"address" sequence. J Med Chem40:1211-8 (1997) [PubMed] Article |
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More Info.: | Get all data from this article, Assay Method |
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Mu-type opioid receptor |
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Name: | Mu-type opioid receptor |
Synonyms: | M-OR-1 | MOR-1 | Mu opioid receptor | Mu-type opioid receptor (Mu) | OPIATE Mu | OPRM1 | OPRM_CAVPO |
Type: | Enzyme Catalytic Domain |
Mol. Mass.: | 11165.58 |
Organism: | GUINEA PIG |
Description: | P97266 |
Residue: | 98 |
Sequence: | YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSI
FTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI
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BDBM50057389 |
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n/a |
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Name | BDBM50057389 |
Synonyms: | Analog of Dynorphin A | CHEMBL408024 |
Type | Small organic molecule |
Emp. Form. | C70H113N19O17 |
Mol. Mass. | 1492.7633 |
SMILES | CC[C@H](C)[C@H](NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1ccccc1)NC(=O)CNC(=O)CNC(=O)[C@@H](N)Cc1ccc(O)cc1)C(=O)NC[C@@H](N)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCCN)C(O)=O |
Structure |
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